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Molecular Cancer

Molecular Cancer is a peer-reviewed journal that focuses on the molecular basis of cancer development and progression. It publishes cutting-edge research articles, reviews, and commentaries that explore the intricate mechanisms underlying tumor biology, including genetic and epigenetic alterations, signaling pathways, and therapeutic strategies. With a multidisciplinary approach, Molecular Cancer provides valuable insights into the molecular complexities of cancer, fostering advancements in diagnosis, treatment, and prevention.

Details
Abbr. Mol Cancer
Publisher Biomed Central
Start 2002
End Continuing
e-ISSN 1476-4598
Country United Kingdom
Language English
Metrics
h-index / Ranks: 754 196
SJR / Ranks: 108 8222
CiteScore / Ranks: 24 64.90
JIF / Ranks: 55 37.3
Recent Articles
1.
Dai J, Lu X, Zhang C, Qu T, Li W, Su J, et al.
Mol Cancer . 2025 Mar; 24(1):79. PMID: 40089784
Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are remarkably effective for treating EGFR-mutant non-small cell lung cancer (NSCLC). However, patients inevitably develop acquired drug resistance, resulting in recurrence or...
2.
Peng W, Shi M, Hu B, Jia J, Li X, Wang N, et al.
Mol Cancer . 2025 Mar; 24(1):78. PMID: 40087758
As promising noninvasive biomarkers, nucleic acids provide great potential to innovate cancer early detection methods and promote subsequent diagnosis to improve the survival rates of patient. Accurate, straightforward and sensitive...
3.
Hyeon D, Nam D, Shin H, Jeong J, Jung E, Cho S, et al.
Mol Cancer . 2025 Mar; 24(1):77. PMID: 40087745
We report proteogenomic analysis of locally advanced cervical cancer (LACC). Exome-seq data revealed predominant alterations of keratinization-TP53 regulation and O-glycosylation-TP53 regulation axes in squamous and adeno-LACC, respectively, compared to in...
4.
Bandi D, Nagaraju G, Sarvesh S, Carstens J, Foote J, Graff E, et al.
Mol Cancer . 2025 Mar; 24(1):76. PMID: 40082968
Background: Oncogenic KRAS mutations occur in nearly, 90% of patients with pancreatic ductal adenocarcinoma (PDAC). Targeting KRAS has been complicated by mutational heterogeneity and rapid resistance. We developed a novel...
5.
Miao K, Zhang A, Yang X, Zhang Y, Lin A, Wang L, et al.
Mol Cancer . 2025 Mar; 24(1):75. PMID: 40075470
Cancer metastasis is the primary cause of cancer-related death, yet the forces that drive cancer cells through various steps and different routes to distinct target organs/tissues remain elusive. In this...
6.
Wan Y, Li G, Cui G, Duan S, Chang S
Mol Cancer . 2025 Mar; 24(1):74. PMID: 40069775
Thyroid cancer as one of the most prevalent malignancies of endocrine system, has raised public concern and more research on its mechanism and treatment. And metabolism-based therapies have advanced rapidly,...
7.
Huang L, Xu R, Chen S, Lin C, Li W, Li S, et al.
Mol Cancer . 2025 Mar; 24(1):73. PMID: 40059153
Abnormal lipid metabolism plays an important role in the development and progression of almost all cancer types, especially hepatocellular carcinoma (HCC) as the liver is the central organ for lipid...
8.
Xie X, Liu W, Yuan Z, Chen H, Mao W
Mol Cancer . 2025 Mar; 24(1):71. PMID: 40057791
Epigenomic modifications-such as DNA methylation, histone acetylation, and histone methylation-and their implications in tumorigenesis, progression, and treatment have emerged as a pivotal field in cancer research. Tumors undergo metabolic reprogramming...
9.
Cheytan T, Schneider M, Wurth R, Schwerd-Kleine P, Gutjahr E, Thewes V, et al.
Mol Cancer . 2025 Mar; 24(1):72. PMID: 40057730
Metastatic breast cancer remains largely incurable, partly due to our incomplete understanding of its intricate underlying mechanisms. Notably, intercellular communication mediated by small extracellular vesicles and particles (sEVPs) has emerged...
10.
Park S, Pylaeva E, Bhuria V, Gambardella A, Schiavoni G, Mougiakakos D, et al.
Mol Cancer . 2025 Mar; 24(1):69. PMID: 40050933
Cancer-associated myeloid cells due to their plasticity play dual roles in both promoting and inhibiting tumor progression. Myeloid cells with immunosuppressive properties play a critical role in anti-cancer immune regulation....