Theresa M Reineke
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Explore the profile of Theresa M Reineke including associated specialties, affiliations and a list of published articles.
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132
Citations
1579
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Recent Articles
1.
Osborn M, Panda S, Reineke T, Tolar J, Nystrom A
Mol Ther
. 2025 Mar;
PMID: 40077969
The skin is the largest organ of the body and forms and serves as the barrier for preventing external material from accessing and damaging internal organs. As the outward interface...
2.
Roy P, Kreofsky N, Santa Chalarca C, Reineke T
Bioconjug Chem
. 2025 Mar;
PMID: 40067683
Successful gene therapies require the efficient delivery of the therapeutic nucleic acids in the target cells, which is a major bottleneck. Our group has demonstrated that quinine-based polymers are effective...
3.
Kreofsky N, Roy P, Reineke T
Bioconjug Chem
. 2024 Oct;
35(11):1762-1778.
PMID: 39467734
Quinine is a promising building block for creating polymer carriers for intracellular nucleic acid delivery. This is due to its ability to bind to genetic material through intercalation and electrostatic...
4.
Roy P, Kreofsky N, Reineke T
Biomacromolecules
. 2024 Sep;
25(10):6693-6707.
PMID: 39324490
Quinine-based polymers have previously demonstrated promising performance in delivering pDNA in cells owing to their electrostatic as well as the nonelectrostatic interactions with pDNA. Herein, we evaluate whether quinine-based polymers...
5.
Prebihalo E, Reineke T
ACS Macro Lett
. 2024 Sep;
13(10):1355-1361.
PMID: 39321342
Pressure-sensitive adhesives occupy a large role in the commercial use of polymers; however, they are typically limited to nondegradable formulations using petroleum-based materials. As the plastic and environmental crises have...
6.
Leyden M, Oviedo F, Saxena S, Kumar R, Le N, Reineke T
Bioconjug Chem
. 2024 Jun;
35(7):897-911.
PMID: 38924453
Cationic polymers offer an alternative to viral vectors in nucleic acid delivery. However, the development of polymer vehicles capable of high transfection efficiency and minimal toxicity has remained elusive, and...
7.
Wouters C, Abed M, Nguyen T, Froehlich C, Roy P, Reineke T, et al.
Anal Chem
. 2024 Jun;
96(25):10302-10312.
PMID: 38873697
Virus detection is highly important; the last several years, since the onset of the SARS-CoV-2 pandemic, have highlighted a weakness in the field: the need for highly specialized and complex...
8.
Dalal R, Oviedo F, Leyden M, Reineke T
Chem Sci
. 2024 May;
15(19):7219-7228.
PMID: 38756796
We present the facile synthesis of a clickable polymer library with systematic variations in length, binary composition, p, and hydrophobicity (clog ) to optimize intracellular pDNA and CRISPR-Cas9 ribonucleoprotein (RNP)...
9.
Prebihalo E, Johnson M, Reineke T
ACS Macro Lett
. 2024 Apr;
13(5):586-591.
PMID: 38666714
Thermoset networks are chemically cross-linked materials that exhibit high heat resistance and mechanical strength; however, the permanently cross-linked system makes end-of-life degradation difficult. Thermosets that are inherently degradable and made...
10.
Barr K, Ohnsorg M, Liberman L, Corcoran L, Sarode A, Nagapudi K, et al.
Bioconjug Chem
. 2024 Mar;
35(4):499-516.
PMID: 38546823
Nanodroplet formation is important to achieve supersaturation of active pharmaceutical ingredients (APIs) in an amorphous solid dispersion. The aim of the current study was to explore how polymer composition, architecture,...