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Biomacromolecules

Biomacromolecules is a leading scientific journal that focuses on the interdisciplinary field of macromolecular science and engineering. It publishes cutting-edge research articles, reviews, and communications that explore the synthesis, characterization, and applications of biomacromolecules, including proteins, nucleic acids, polysaccharides, and synthetic polymers. With a broad scope and high impact factor, Biomacromolecules serves as a vital resource for researchers and professionals in the fields of biotechnology, materials science, bioengineering, and drug delivery.
Details
Abbr. Biomacromolecules
Publisher American Chemical Society
Start 2000
End Continuing
Frequency Bimonthly, 2001-
p-ISSN 1525-7797
e-ISSN 1526-4602
Country United States
Language English
Specialties Biochemistry
Biology
Molecular Biology
Metrics
h-index / Ranks: 353 252
SJR / Ranks: 2723 1232
CiteScore / Ranks: 1136 11.10
JIF / Ranks: 1060 6.2
Recent Articles
1.
Multiple Pendants-Bearing Triglucosides for Membrane Protein Studies: Effects of Pendant Length and Number on Micelle Interior Hydration and Protein Stability
Sadaf A, Yun H, Lee H, Stanfield S, Lan B, Salomon K, et al.
Biomacromolecules . 2025 Mar; PMID: 40087026
Membrane proteins play central roles in cell physiology and are the targets of over 50% of FDA-approved drugs. In the present study, we prepared single alkyl-chained triglucosides decorated with multiple...
2.
Side-Functionalization of Poly(l-methionine) for Ice Control
Niu Q, Shang K, Han H, Chen B, Zhu K, Ren L, et al.
Biomacromolecules . 2025 Mar; PMID: 40084906
Controlling ice growth is crucial during the cryopreservation of cells, but the current application of small molecules as cryoprotectants still remains a challenge. Inspired by structures of natural antifreeze (glyco)proteins,...
3.
Regulating the Characteristic Networks of Biodegradable Poly(l-malic acid-ε-caprolactone) Shape-Memory Materials: From Plastics to Elastomers
Song J, Jiao J, Jiang C, Qiu Y, Wu D
Biomacromolecules . 2025 Mar; PMID: 40080423
Developing new biodegradable polyesters with well-defined structures is of interest. We reported an attractive two-component aliphatic polyester-based thermoset, which was prepared via the esterification of biomass-derived l-malic acid oligomers and...
4.
In Vitro Evaluation of Gelatin-Based Hydrogels as Potential Fillers for Corneal Wounds
Romo-Valera C, Appel E, Etxebarria J, Arluzea J, Andollo N
Biomacromolecules . 2025 Mar; PMID: 40079491
Corneal persistent epithelial defects are common ophthalmic injuries that can cause significant visual and structural damage. While diagnosis is straightforward, treatment remains challenging. Noninvasive therapies like eye drops are preferred,...
5.
Synthetic Strategy to Build High-Molecular-Weight Poly(L-tyrosine) and Its Unexplored β-Sheet Block Copolymer Nanoarchitectures
Kambale P, Nisal R, Jayakannan M
Biomacromolecules . 2025 Mar; PMID: 40074672
Synthesis of high-molecular-weight polypeptides and their block copolymer macromolecular architectures from β-sheet-promoting L-amino acids is still an unresolved problem. Here, an elegant steric hindrance-assisted ring-opening polymerization (SHAROP) strategy is introduced...
6.
Accelerated Missense Mutation Identification in Intrinsically Disordered Proteins Using Deep Learning
Seth S, Bhattacharya A
Biomacromolecules . 2025 Mar; PMID: 40072940
We use a combination of Brownian dynamics (BD) simulation results and deep learning (DL) strategies for the rapid identification of large structural changes caused by missense mutations in intrinsically disordered...
7.
Fabrication of pH- and Ultrasound-Responsive Polymeric Micelles: The Effect of Amphiphilic Block Copolymers with Different Hydrophilic/Hydrophobic Block Ratios for Self-Assembly and Controlled Drug Release
Wei H, Liu M, Wang T, Shih M, Yu J, Yeh Y
Biomacromolecules . 2025 Mar; PMID: 40067950
Stimuli-responsive polymeric vehicles can change their physical or chemical properties when exposed to internal or external triggers, enabling precise spatiotemporal control of drug release. Nevertheless, systematic research is lacking in...
8.
Surface-Vinylated Cellulose Nanocrystals as Cross-Linkers for Hydrogel Composites
Kroger M, Paakkonen T, Fliri L, Lehrhofer A, Sulaeva I, Potthast A, et al.
Biomacromolecules . 2025 Mar; PMID: 40067881
Cellulose nanocrystal (CNC) fillers have been shown to significantly improve the performance of polymer composites and hydrogels, elevating both strength and toughness. Polymer grafting from the surface of the nanocrystals...
9.
Correction to "Tumor-pH-Sensitive PLLA-Based Microsphere with Acid Cleavable Acetal Bonds on the Backbone for Efficient Localized Chemotherapy"
Li J, Zhang X, Zhao M, Wu L, Luo K, Pu Y, et al.
Biomacromolecules . 2025 Mar; PMID: 40064614
No abstract available.
10.
Hybrid Anticancer Peptide Synergistically Improving Cancer Cell Uptake and Inducing Apoptosis Mediated by Membrane Fusion
Jia Z, Wang D, Wu R, Shi H, Zhu T, Li J, et al.
Biomacromolecules . 2025 Mar; PMID: 40063925
Anticancer peptides (ACPs) have exhibited tremendous potential in tumor treatment. However, low peptide delivery efficiency limits some ACPs' clinical application. Herein, we designed a hybrid peptide named AFP-KLA and investigated...