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Yemin Liu

Explore the profile of Yemin Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 219
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Recent Articles
1.
Liu Y, Liu F
Rev Esp Enferm Dig . 2024 Sep; 119. PMID: 39235207
Splenic ectopic pregnancy refers to the implantation of fertilized ovum in the spleen, which occurs extremely rare. Due to the abundance of splenic blood and its fragile texture, the lethality...
2.
North J, Saari-Nordhaus R, Doddridge G, Seefeldt M, Young D, Liu Y
AAPS PharmSciTech . 2024 Apr; 25(4):76. PMID: 38580881
For liquid drug products, e.g., solutions or suspensions for oral or parenteral dosing, stability needs to be demonstrated in primary packaging during storage and in dosing devices during in-use periods...
3.
Wilson S, Farabaugh J, Liu Y, Liu Z, Meyers R, Santangelo M, et al.
AAPS J . 2024 Apr; 26(3):43. PMID: 38575754
Medication administration via enteral feeding tubes (EFT) is a necessary practice for patients unable to swallow oral dosage forms due to a medical condition or treatment that affects the ability...
4.
Lee C, Liu Y, Reineke T
ACS Macro Lett . 2022 May; 1(12):1388-1392. PMID: 35607112
Herein, the synthesis and characterization of two glucose-based degradable poly(ester amines), and , are described. Data from gel shift assays, PicoGreen dye exclusion, and dynamic light scattering studies reveals that...
5.
Doddridge G, Hong E, Tan D, Liu Y
AAPS PharmSciTech . 2022 May; 23(5):132. PMID: 35501618
Compatibility and in-use stability screening studies are required for dosing vehicle selection based on the FDA's guidance, "Use of Liquids and/or Soft Foods as Vehicles for Drug Administration: General Considerations...
6.
Alaarg A, Menon R, Rizzo D, Liu Y, Bien J, Elkinton T, et al.
Clin Transl Sci . 2021 Aug; 15(1):244-254. PMID: 34416076
This work presents an end-to-end approach for assessing the absolute bioavailability of highly hydrophobic, poorly water-soluble compounds that exhibit high nonspecific binding using venetoclax as a model drug. The approach...
7.
Liu Y, Doddi J, Zheng Y, Ho V, Pheil M, Shi Y
Appl Spectrosc . 2019 Oct; 74(1):108-115. PMID: 31617385
Transmission Raman spectroscopy is an emerging technique, capable of quantitative analysis of drug products nondestructively using a multivariate data analysis approach. We developed and validated a chemometric method to quantify...
8.
Zhao X, Liu Y, Song J, Yong H, Li L, Shen Y, et al.
J Drug Target . 2012 Jan; 20(3):281-9. PMID: 22214439
To design a clinically viable small interfering RNA (siRNA) formulation, it is essential to understand the in vivo siRNA delivery mechanism during the product development. However, majority of reported siRNA...
9.
Tranter M, Liu Y, He S, Gulick J, Ren X, Robbins J, et al.
Mol Ther . 2011 Dec; 20(3):601-8. PMID: 22186793
Using a new class of nontoxic and degradable glycopolymer-based vehicles termed poly(glycoamidoamine)s, we demonstrate virus-like delivery efficacy of oligodeoxynucleotide (ODN) decoys to cardiomyoblasts (H9c2), primary cardiomyocytes, and the mouse heart....
10.
Liu Y, Reineke T
Biomacromolecules . 2010 Jan; 11(2):316-25. PMID: 20058913
Poly(glycoamidoamine)s (PGAAs) are a group of efficient and degradable gene delivery vehicles that consist of three main functionalities: carbohydrate groups, secondary amines, and amide bonds. Herein, we have created nonhydroxylated...