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Yaoying Wu

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Articles 23
Citations 479
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Recent Articles
1.
Shetty S, Wu Y, Lloyd C, Mehta N, Liu Y, Woodruff M, et al.
Adv Healthc Mater . 2024 Aug; 14(5):e2401444. PMID: 39113323
IL-1β is a principal proinflammatory cytokine underlying multiple local and systemic chronic inflammatory conditions including psoriasis, rheumatoid arthritis, inflammatory bowel disease, and type 2 diabetes. Passive immunotherapies and biologic drugs...
2.
Winston T, Song Y, Shi H, Yang J, Alsudais M, Kontaridis M, et al.
Adv Sci (Weinh) . 2024 May; 11(28):e2308975. PMID: 38757640
Over the past decades, mesenchymal stromal cells (MSCs) have been extensively investigated as a potential therapeutic cell source for the treatment of various disorders. Differentiation of MSCs from human induced...
3.
Zareein A, Mahmoudi M, Jadhav S, Wilmore J, Wu Y
Biomater Sci . 2024 Mar; 12(8):1981-2006. PMID: 38456305
B cell immunity has a penetrating effect on human health and diseases. Therapeutics aiming to modulate B cell immunity have achieved remarkable success in combating infections, autoimmunity, and malignancies. However,...
4.
Liu Y, Suarez-Arnedo A, Shetty S, Wu Y, Schneider M, Collier J, et al.
Adv Sci (Weinh) . 2023 Feb; 10(11):e2204882. PMID: 36762570
Microporous annealed particle scaffolds (MAPS) are a new class of granular materials generated through the interlinking of tunable microgels, which produce an interconnected network of void space. These microgel building...
5.
Kelly S, Votaw N, Cossette B, Wu Y, Shetty S, Shores L, et al.
Sci Adv . 2022 Nov; 8(47):eabq4120. PMID: 36417519
Urinary tract infections (UTIs) are a major public health problem affecting millions of individuals each year. Recurrent UTIs are managed by long-term antibiotic use, making the alarming rise of antibiotic...
6.
Chen J, Fries C, Berendam S, Rodgers N, Roe E, Wu Y, et al.
Sci Adv . 2022 Sep; 8(38):eabq0273. PMID: 36149967
To develop vaccines for certain key global pathogens such as HIV, it is crucial to elicit both neutralizing and non-neutralizing Fc-mediated effector antibody functions. Clinical evidence indicates that non-neutralizing antibody...
7.
Wu Y, Wen H, Bernstein Z, Hainline K, Blakney T, Congdon K, et al.
Sci Adv . 2022 Jul; 8(29):eabm7833. PMID: 35857833
Subunit vaccines inducing antibodies against tumor-specific antigens have yet to be clinically successful. Here, we use a supramolecular α-helical peptide nanofiber approach to design epitope-specific vaccines raising simultaneous B cell,...
8.
Votaw N, Collier L, Curvino E, Wu Y, Fries C, Ojeda M, et al.
Biomaterials . 2021 Apr; 273:120825. PMID: 33901731
Biomaterials capable of inducing immune responses with minimal associated inflammation are of interest in applications ranging from tissue repair to vaccines. Here we report the design of self-assembling randomized polypeptide...
9.
Kelly S, Cossette B, Varadhan A, Wu Y, Collier J
ACS Biomater Sci Eng . 2021 Mar; 7(5):1876-1888. PMID: 33775089
Effective sublingual peptide immunization requires overcoming challenges of both delivery and immunogenicity. Mucosal adjuvants, such as cyclic-dinucleotides (CDN), can promote sublingual immune responses but must be codelivered with the antigen...
10.
Kelly S, Opolot E, Wu Y, Cossette B, Varadhan A, Collier J
Adv Healthc Mater . 2021 Feb; 10(6):e2001614. PMID: 33634607
Widespread vaccination is essential to global health. Significant barriers exist to improving vaccine coverage in lower- and middle-income countries, including the costly requirements for cold-chain distribution and trained medical personnel...