Tamara R Castaneda
Overview
Explore the profile of Tamara R Castaneda including associated specialties, affiliations and a list of published articles.
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27
Citations
1066
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0
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Recent Articles
1.
Vacca M, Kamzolas I, Harder L, Oakley F, Trautwein C, Hatting M, et al.
Nat Metab
. 2024 Jun;
6(6):1178-1196.
PMID: 38867022
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease, encompasses steatosis and metabolic dysfunction-associated steatohepatitis (MASH), leading to cirrhosis and hepatocellular carcinoma. Preclinical MASLD research is...
2.
Erdogan B, Michel M, Matthes J, Castaneda T, Christen U, Arioglu-Inan E, et al.
Front Pharmacol
. 2023 Mar;
14:1118730.
PMID: 36891264
Diabetes often leads to lower urinary tract dysfunction. The most frequently assessed parameter of urinary bladder dysfunction in animal models of diabetes is an enlargement of the bladder, which is...
3.
Yesilyurt Z, Matthes J, Hintermann E, Castaneda T, Elvert R, Beltran-Ornelas J, et al.
Front Physiol
. 2022 Aug;
13:923555.
PMID: 36003651
The urinary bladder is markedly enlarged in the type 1 diabetes mellitus model of streptozotocin-injected rats, which may contribute to the frequent diabetic uropathy. Much less data exists for models...
4.
Mishra A, Castaneda T, Bader E, Elshorst B, Cummings S, Scherer P, et al.
Adv Sci (Weinh)
. 2020 Dec;
7(24):2002997.
PMID: 33344141
Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease that can lead to irreversible liver cirrhosis and cancer. Early diagnosis of NASH is vital to detect disease...
5.
Castaneda T, Mendez M, Davison I, Elvert R, Schwahn U, Boldina G, et al.
J Pharmacol Exp Ther
. 2020 Nov;
376(2):190-203.
PMID: 33203659
As a gut-restricted, nonabsorbed therapy, polymeric bile acid sequestrants (BAS) play an important role in managing hyperlipidemia and hyperglycemia. Similarly, nonabsorbable sequestrants of dietary phosphate have been used for the...
6.
Schmoll D, Ziegler N, Viollet B, Foretz M, Even P, Azzout-Marniche D, et al.
Hepatol Commun
. 2020 Jul;
4(7):1056-1072.
PMID: 32626837
The worldwide obesity and type 2 diabetes epidemics have led to an increase in nonalcoholic fatty liver disease (NAFLD). NAFLD covers a spectrum of hepatic pathologies ranging from simple steatosis...
7.
Romacho T, Sell H, Indrakusuma I, Roehrborn D, Castaneda T, Jelenik T, et al.
Am J Physiol Endocrinol Metab
. 2020 Jan;
318(5):E590-E599.
PMID: 31891536
Besides a therapeutic target for type 2 diabetes, dipeptidyl peptidase 4 (DPP4) is an adipokine potentially upregulated in human obesity. We aimed to explore the role of adipocyte-derived DPP4 in...
8.
Grandoch M, Flogel U, Virtue S, Maier J, Jelenik T, Kohlmorgen C, et al.
Nat Metab
. 2019 Oct;
1(5):546-559.
PMID: 31602424
Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix,...
9.
Jelenik T, Dille M, Muller-Luhlhoff S, Kabra D, Zhou Z, Binsch C, et al.
Mol Metab
. 2018 Jul;
16:126-138.
PMID: 29980484
Objective: Post-traumatic stress disorder (PTSD) increases type 2 diabetes risk, yet the underlying mechanisms are unclear. We investigated how early-life exposure to chronic stress affects long-term insulin sensitivity. Methods: C57Bl/6J...
10.
Heinrich G, Russo L, Castaneda T, Pfeiffer V, Ghadieh H, Ghanem S, et al.
J Biol Chem
. 2016 Mar;
291(21):11124-32.
PMID: 27002145
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) promotes hepatic insulin clearance. Consistently, mice with null mutation of Ceacam1 (Cc1(-/-)) exhibit impaired insulin clearance with increased lipid production in liver and...