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Hadi Al-Hasani

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Articles 118
Citations 1934
Followers 0
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Recent Articles
1.
Turewicz M, Skagen C, Hartwig S, Majda S, Thedinga K, Herwig R, et al.
Nat Commun . 2025 Feb; 16(1):1570. PMID: 39939313
Insulin is a pleiotropic hormone that elicits its metabolic and mitogenic actions through numerous rapid and reversible protein phosphorylations. The temporal regulation of insulin's intracellular signaling cascade is highly complex...
2.
Pesta D, Anadol-Schmitz E, Sarabhai T, Op den Kamp Y, Gancheva S, Trinks N, et al.
Sci Adv . 2025 Jan; 11(1):eadr8849. PMID: 39742483
The athlete's paradox states that intramyocellular triglyceride accumulation associates with insulin resistance in sedentary but not in endurance-trained humans. Underlying mechanisms and the role of muscle lipid distribution and composition...
3.
Mastrototaro L, Apostolopoulou M, Hartwig S, Strassburger K, Lipaeva P, Trinks N, et al.
EBioMedicine . 2024 Dec; 110:105471. PMID: 39626509
Background: High-intensity interval training (HIIT) has been shown to improve cardiorespiratory fitness (V˙O max) but may ameliorate insulin sensitivity only in insulin-resistant humans. It is yet unclear whether these benefits...
4.
Zaharia O, Strassburger K, Knebel B, Binsch C, Kupriyanova Y, Moser C, et al.
Diabetes Metab Syndr . 2024 Oct; 18(10):103137. PMID: 39427597
Aims: We examined the association of the G allele in the single-nucleotide polymorphism (SNP) rs738409 in the third exon of patatin-like phospholipase domain-containing 3 gene (PNPLA3) gene, with chronic kidney...
5.
Lenihan-Geels G, Garcia Carrizo F, Leer M, Gohlke S, Oster M, Pohle-Kronawitter S, et al.
J Cachexia Sarcopenia Muscle . 2024 Jul; 15(5):1772-1784. PMID: 39010299
Background: The ability of skeletal muscle to respond adequately to changes in nutrient availability, known as metabolic flexibility, is essential for the maintenance of metabolic health and loss of flexibility...
6.
Geiser A, Currie S, Al-Hasani H, Chadt A, McConnell G, Gould G
J Cell Sci . 2024 Jul; 137(20). PMID: 38958032
Cellular heterogeneity is a well-accepted feature of tissues, and both transcriptional and metabolic diversity have been revealed by numerous approaches, including optical imaging. However, the high magnification objective lenses needed...
7.
Erkens R, Duse D, Brum A, Chadt A, Becher S, Siragusa M, et al.
Br J Pharmacol . 2024 Jul; 181(21):4174-4194. PMID: 38956895
Background And Purpose: Remote ischaemic preconditioning (rIPC) for cardioprotection is severely impaired in diabetes, and therapeutic options to restore it are lacking. The vascular endothelium plays a key role in...
8.
Dietzsch A, Al-Hasani H, Altschmied J, Bottermann K, Brendler J, Haendeler J, et al.
Signal Transduct Target Ther . 2024 Apr; 9(1):103. PMID: 38664368
Obesity is one of the diseases with severe health consequences and rapidly increasing worldwide prevalence. Understanding the complex network of food intake and energy balance regulation is an essential prerequisite...
9.
Springer C, Binsch C, Weide D, Toska L, Cremer A, Backes H, et al.
Diabetes . 2024 Apr; 73(7):1058-1071. PMID: 38608276
Article Highlights:
10.
Nikolic A, Fahlbusch P, Riffelmann N, Wahlers N, Jacob S, Hartwig S, et al.
iScience . 2024 Mar; 27(3):109276. PMID: 38450153
Chronic stress episodes increase metabolic disease risk even after recovery. We propose that persistent stress detrimentally impacts hepatic metabolic reprogramming, particularly mitochondrial function. In male C57BL/6 mice chronic variable stress...