Matthias H Tschop
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Explore the profile of Matthias H Tschop including associated specialties, affiliations and a list of published articles.
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324
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15285
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Recent Articles
1.
Muller T, Adriaenssens A, Ahren B, Bluher M, Birkenfeld A, Birkenfeld A, et al.
Mol Metab
. 2025 Mar;
95:102118.
PMID: 40024571
Background: Glucose-dependent insulinotropic polypeptide (GIP) was the first incretin identified and plays an essential role in the maintenance of glucose tolerance in healthy humans. Until recently GIP had not been...
2.
Rubino F, Cummings D, Eckel R, Cohen R, Wilding J, Brown W, et al.
Lancet Diabetes Endocrinol
. 2025 Jan;
13(3):221-262.
PMID: 39824205
No abstract available.
3.
Miranda-Cervantes A, Fritzen A, Raun S, Hodek O, Moller L, Johann K, et al.
Nat Commun
. 2025 Jan;
16(1):345.
PMID: 39746949
Metabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. Exercise enhances metabolic flexibility, making it an...
4.
Chen B, Yu X, Horvath-Diano C, Ortuno M, Tschop M, Jastreboff A, et al.
Cell Metab
. 2024 Oct;
36(10):2173-2189.
PMID: 39357509
Readily available nutrient-rich foods exploit our inherent drive to overconsume, creating an environment of overnutrition. This transformative setting has led to persistent health issues, such as obesity and metabolic syndrome....
5.
Sanchez-Garrido M, Serrano-Lopez V, Ruiz-Pino F, Vazquez M, Rodriguez-Martin A, Torres E, et al.
Nat Commun
. 2024 Oct;
15(1):8498.
PMID: 39353946
Polycystic ovary syndrome (PCOS) is a heterogeneous condition, defined by oligo-/anovulation, hyper-androgenism and/or polycystic ovaries. Metabolic complications are common in patients suffering PCOS, including obesity, insulin resistance and type-2 diabetes,...
6.
Contreras R, Gruber T, Gonzalez-Garcia I, Schriever S, De Angelis M, Mallet N, et al.
Mol Metab
. 2024 Sep;
90:102033.
PMID: 39304061
With age, metabolic perturbations accumulate to elevate our obesity burden. While age-onset obesity is mostly driven by a sedentary lifestyle and high calorie intake, genetic and epigenetic factors also play...
7.
Sachs S, Gotz A, Finan B, Feuchtinger A, DiMarchi R, Doring Y, et al.
Cardiovasc Diabetol
. 2024 Sep;
23(1):341.
PMID: 39267039
No abstract available.
8.
Kusminski C, Perez-Tilve D, Muller T, DiMarchi R, Tschop M, Scherer P
Cell
. 2024 Jul;
187(15):3829-3853.
PMID: 39059360
For more than a century, physicians have searched for ways to pharmacologically reduce excess body fat. The tide has finally turned with recent advances in biochemically engineered agonists for the...
9.
Gutgesell R, Nogueiras R, Tschop M, Muller T
Diabetes Ther
. 2024 Apr;
15(5):1069-1084.
PMID: 38573467
The discovery of long-acting incretin receptor agonists represents a major stride forward in tackling the dual epidemic of obesity and diabetes. Here we outline the evolution of incretin-based pharmacotherapy, from...
10.
Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker D, et al.
Mol Metab
. 2024 Mar;
83:101915.
PMID: 38492844
Objective: The glucose-dependent insulinotropic polypeptide (GIP) decreases body weight via central GIP receptor (GIPR) signaling, but the underlying mechanisms remain largely unknown. Here, we assessed whether GIP regulates body weight...