Sung Wook Yi
Overview
Explore the profile of Sung Wook Yi including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
184
Followers
0
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Recent Articles
1.
Ha M, Yi S, Paek S
Antibiotics (Basel)
. 2020 Oct;
9(10).
PMID: 33081148
The widespread and uncontrollable emergence of antibiotic-resistant bacteria, especially methicillin-resistant , has promoted a wave of efforts to discover a new generation of antibiotics that prevent or treat bacterial infections...
2.
Gosschalk J, Chang C, Sue C, Siegel S, Wu C, Kattke M, et al.
Sci Rep
. 2020 May;
10(1):8520.
PMID: 32444661
Sortase enzymes are attractive antivirulence drug targets that attach virulence factors to the surface of Staphylococcus aureus and other medically significant bacterial pathogens. Prior efforts to discover a useful sortase...
3.
Chan A, Yi S, Weiner E, Amer B, Sue C, Wereszczynski J, et al.
Chem Biol Drug Des
. 2017 Feb;
90(3):327-344.
PMID: 28160417
Staphylococcus aureus is a leading cause of hospital-acquired infections in the USA and is a major health concern as methicillin-resistant S. aureus and other antibiotic-resistant strains are common. Compounds that...
4.
Jacobitz A, Naziga E, Yi S, McConnell S, Peterson R, Jung M, et al.
J Phys Chem B
. 2016 Apr;
120(33):8302-12.
PMID: 27109553
Many species of Gram-positive bacteria use sortase enzymes to assemble long, proteinaceous pili structures that project from the cell surface to mediate microbial adhesion. Sortases construct highly stable structures by...
5.
Chan A, Yi S, Terwilliger A, Maresso A, Jung M, Clubb R
J Biol Chem
. 2015 Sep;
290(42):25461-74.
PMID: 26324714
The endospore forming bacterium Bacillus anthracis causes lethal anthrax disease in humans and animals. The ability of this pathogen to replicate within macrophages is dependent upon the display of bacterial...
6.
Jacobitz A, Wereszczynski J, Yi S, Amer B, Huang G, Nguyen A, et al.
J Biol Chem
. 2014 Feb;
289(13):8891-902.
PMID: 24519933
Sortase cysteine transpeptidases covalently attach proteins to the bacterial cell wall or assemble fiber-like pili that promote bacterial adhesion. Members of this enzyme superfamily are widely distributed in Gram-positive bacteria...
7.
Chan A, Wereszczynski J, Amer B, Yi S, Jung M, McCammon J, et al.
Chem Biol Drug Des
. 2013 May;
82(4):418-28.
PMID: 23701677
Staphylococcus aureus is the leading cause of hospital-acquired infections in the United States. The emergence of multidrug-resistant strains of S. aureus has created an urgent need for new antibiotics. Staphylococcus...
8.
Jung M, Perez F, Regan C, Yi S, Perron Q
Angew Chem Int Ed Engl
. 2013 Jan;
52(7):2060-2.
PMID: 23315953
No abstract available.
9.
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors
Suree N, Yi S, Thieu W, Marohn M, Damoiseaux R, Chan A, et al.
Bioorg Med Chem
. 2009 Sep;
17(20):7174-85.
PMID: 19781950
Methicillin resistant Staphylococcus aureus (MRSA) is a major health problem that has created a pressing need for new antibiotics. Compounds that inhibit the S. aureus SrtA sortase may function as...
10.
Yi S, Jain P, Ajmera M, Kaulagari S, Topper M, Anderson L, et al.
Adv Exp Med Biol
. 2009 Apr;
611:553-4.
PMID: 19400310
No abstract available.