Suheeta Roy
Overview
Explore the profile of Suheeta Roy including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
539
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Recent Articles
1.
Fernandez M, Roy S, Vergara-Jimenez M
Nutr Res
. 2023 Oct;
20(6):837-849.
PMID: 37817373
The effects of resistant starch (RS) and cholestyramine (CHY) on cholesterol metabolism were tested in guinea pigs. Animals were fed cellulose (14 g 100 g ) (control diet) RS (10...
2.
Sleiman M, Roy S, Gao A, Sadler M, Von Alvensleben G, Li H, et al.
Science
. 2022 Sep;
377(6614):eabo3191.
PMID: 36173858
DNA variants that modulate life span provide insight into determinants of health, disease, and aging. Through analyses in the UM-HET3 mice of the Interventions Testing Program (ITP), we detected a...
3.
Williams E, Pfister N, Roy S, Statzer C, Haverty J, Ingels J, et al.
Cell Syst
. 2021 Oct;
13(1):43-57.e6.
PMID: 34666007
We profiled the liver transcriptome, proteome, and metabolome in 347 individuals from 58 isogenic strains of the BXD mouse population across age (7 to 24 months) and diet (low or...
4.
Roy S, Sleiman M, Jha P, Ingels J, Chapman C, McCarty M, et al.
Nat Metab
. 2021 Sep;
3(9):1217-1227.
PMID: 34552269
How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in...
5.
Ashbrook D, Arends D, Prins P, Mulligan M, Roy S, Williams E, et al.
Cell Syst
. 2021 Jan;
12(3):235-247.e9.
PMID: 33472028
The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to...
6.
Sandoval-Sierra J, Helbing A, Williams E, Ashbrook D, Roy S, Williams R, et al.
Aging Cell
. 2020 Aug;
19(9):e13207.
PMID: 32790008
DNA methylation (DNAm) is shaped by genetic and environmental factors and modulated by aging. Here, we examine interrelations between epigenetic aging, body weight (BW), and life span in 12 isogenic...
7.
Hook M, Roy S, Williams E, Sleiman M, Mozhui K, Nelson J, et al.
Biochim Biophys Acta Mol Basis Dis
. 2018 Feb;
1864(9 Pt A):2718-2732.
PMID: 29410319
Aging is a complex and highly variable process. Heritability of longevity among humans and other species is low, and this finding has given rise to the idea that it may...
8.
Roy S, Hyogo H, Yadav S, Wu M, Jelicks L, Locker J, et al.
Hepatology
. 2005 Mar;
41(4):887-95.
PMID: 15793852
Human obesity is associated with abnormal hepatic cholesterol homeostasis and resistance to leptin action. Because leptin administration to rodents promotes the biliary elimination of plasma cholesterol, this study was designed...
9.
Villena J, Roy S, Sarkadi-Nagy E, Kim K, Sul H
J Biol Chem
. 2004 Sep;
279(45):47066-75.
PMID: 15337759
We have used rat cDNA microarrays to identify adipocyte-specific genes that could play an important role in adipocyte differentiation or function. Here, we report the cloning and identification of a...
10.
Hyogo H, Roy S, Cohen D
J Lipid Res
. 2003 Apr;
44(6):1232-40.
PMID: 12671032
The absence of leptin due to the ob mutation leads to obesity and confers resistance to diet-induced cholesterol gallstone formation in otherwise susceptible C57BL/6J mice. To investigate contributions of obesity...