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Stephanie Hausler

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Articles 16
Citations 384
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Recent Articles
1.
Grossenbacher P, Essers M, Moser J, Singer S, Hausler S, Stieger B, et al.
RSC Adv . 2022 Nov; 12(44):28306-28317. PMID: 36320493
Antibodies are immensely useful tools for biochemical research and have found application in numerous protein detection and purification methods. Moreover, monoclonal antibodies are increasingly utilised as therapeutics or, conjugated to...
2.
Leuenberger M, Hausler S, Hohn V, Euler A, Stieger B, Lochner M
J Pharmacol Exp Ther . 2021 Mar; 377(3):346-357. PMID: 33782042
Bile salts, such as cholate, glycocholate, taurocholate, and glycochenodeoxycholate, are taken up from the portal blood into hepatocytes via transporters, such as the Na-taurocholate-cotransporting polypeptide (NTCP) and organic anion-transporting polypeptides...
3.
Eshmuminov D, Schuler M, Becker D, Borrego L, Mueller M, Hagedorn C, et al.
Surgery . 2021 Jan; 169(4):894-902. PMID: 33422346
Background: Long-term ex situ liver perfusion may rescue injured grafts. Little is known about bile flow during long-term perfusion. We report the development of a bile stimulation protocol and motivate...
4.
Zhang L, Gui T, Console L, Scalise M, Indiveri C, Hausler S, et al.
J Biol Chem . 2020 Dec; 296:100204. PMID: 33334877
The carnitine/organic cation transporter novel 2 (OCTN2) is responsible for the cellular uptake of carnitine in most tissues. Being a transmembrane protein OCTN2 must interact with the surrounding lipid microenvironment...
5.
Krajnc E, Visentin M, Gai Z, Stieger B, Samodelov S, Hausler S, et al.
J Pharmacol Exp Ther . 2020 Aug; 375(2):239-246. PMID: 32848075
Mitochondrial damage is considered a hallmark of drug-induced liver injury (DILI). However, despite the common molecular etiology, the evolution of the injury is usually unpredictable, with some cases that are...
6.
Gai Z, Gui T, Alecu I, Lone M, Hornemann T, Chen Q, et al.
Liver Int . 2019 Dec; 40(4):844-859. PMID: 31883408
Background & Aims: Patients with non-alcoholic fatty liver disease (NAFLD) exhibit higher levels of plasma 1-deoxysphingolipids than healthy individuals. The aim of this study was to investigate the role of...
7.
Lozano I, Bauer M, Wulkersdorfer B, Traxl A, Philippe C, Weber M, et al.
Mol Pharm . 2019 Dec; 17(1):316-326. PMID: 31790256
P-Glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) in the canalicular membrane of hepatocytes mediate the biliary excretion of drugs and drug metabolites. To measure hepatic ABCB1 and ABCG2 activity,...
8.
Samodelov S, Visentin M, Gai Z, Hausler S, Kullak-Ublick G
Antimicrob Agents Chemother . 2019 Oct; 63(12). PMID: 31591120
The polymixin colistin represents a last resort antibiotic for multidrug resistant infections, but its use is limited by the frequent onset of acute drug-induced kidney injury (DIKI). It is essential...
9.
Visentin M, Torozi A, Gai Z, Hausler S, Li C, Hiller C, et al.
Drug Metab Dispos . 2018 May; 46(8):1129-1136. PMID: 29794161
[F]fluorocholine is the fluorinated analog of [C]choline and is used in positron emission tomography to monitor tumor metabolic activity. Although important to optimize its use and expand the clinical indications,...
10.
Gai Z, Visentin M, Gui T, Zhao L, Thasler W, Hausler S, et al.
Mol Pharmacol . 2018 May; 94(2):802-811. PMID: 29743187
Inflammation has a recognized role in nonalcoholic fatty liver disease (NAFLD) progression. In the present work, we studied the effect of high-fat diet (HFD) on arachidonic acid metabolism in the...