Sophia L Samodelov
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Explore the profile of Sophia L Samodelov including associated specialties, affiliations and a list of published articles.
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25
Citations
416
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Recent Articles
1.
Chodup P, Samodelov S, Visentin M, Kullak-Ublick G
Liver Int
. 2025 Jan;
45(2):e70002.
PMID: 39853863
Targeted therapies and immunotherapies have shown great promise as best-in-class treatments for several cancers with respect to efficacy and safety. While liver test abnormalities are rather common in patients treated...
2.
Samodelov S, Gai Z, De Luca F, Haldimann K, Hobbie S, Muller D, et al.
Sci Rep
. 2024 Jul;
14(1):16444.
PMID: 39013979
Colistin is a polymyxin antibiotic currently experiencing renewed clinical interest due to its efficacy in the treatment of multidrug resistant (MDR) bacterial infections. The frequent onset of acute dose-dependent kidney...
3.
Andres J, Schmunk L, Grau-Enguix F, Braguy J, Samodelov S, Blomeier T, et al.
Plant J
. 2024 Mar;
118(4):927-939.
PMID: 38525669
Gibberellins (GAs) are major regulators of developmental and growth processes in plants. Using the degradation-based signaling mechanism of GAs, we have built transcriptional regulator (DELLA)-based, genetically encoded ratiometric biosensors as...
4.
Grove J, Stephens C, Lucena M, Andrade R, Weber S, Gerbes A, et al.
Diagn Progn Res
. 2023 Sep;
7(1):18.
PMID: 37697410
A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative's...
5.
Gai Z, Samodelov S, Alecu I, Hornemann T, Grove J, Aithal G, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769329
Sphingolipids are exceptionally diverse, comprising hundreds of unique species. The bulk of circulating sphingolipids are synthesized in the liver, thereby plasma sphingolipid profiles represent reliable surrogates of hepatic sphingolipid metabolism...
6.
Rausch M, Samodelov S, Visentin M, Kullak-Ublick G
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430444
The nuclear receptor farnesoid X receptor (FXR, NR1H4) is a bile acid (BA) sensor that links the enterohepatic circuit that regulates BA metabolism and elimination to systemic lipid homeostasis. Furthermore,...
7.
Sutter M, Console L, Fahner A, Samodelov S, Gai Z, Ciarimboli G, et al.
Biochem Pharmacol
. 2022 May;
201:115100.
PMID: 35635891
No abstract available.
8.
Sutter M, Console L, Fahner A, Samodelov S, Gai Z, Ciarimboli G, et al.
Biochem Pharmacol
. 2021 Nov;
194:114840.
PMID: 34774844
The human organic cation transporter 2 (OCT2) is a multispecific transporter with cholesterol-dependent allosteric features. The present work elucidates the role of evolutionarily conserved cholesterol recognition/interaction amino acid consensus sequences...
9.
Braguy J, Samodelov S, Andres J, Ochoa-Fernandez R, Al-Babili S, Zurbriggen M
Methods Mol Biol
. 2021 May;
2309:201-218.
PMID: 34028689
Understanding the biological background of strigolactone (SL) structural diversity and the SL signaling pathway at molecular level requires quantitative and sensitive tools that precisely determine SL dynamics. Such biosensors may...
10.
Niemeyer M, Castillo E, Ihling C, Iacobucci C, Wilde V, Hellmuth A, et al.
Nat Commun
. 2021 Mar;
12(1):1768.
PMID: 33723268
No abstract available.