Antimicrobial Agents and Chemotherapy
Overview
Antimicrobial Agents and Chemotherapy is a peer-reviewed scientific journal that focuses on the study of antimicrobial agents, their mechanisms of action, and their use in the treatment of infectious diseases. It covers a wide range of topics including the development of new antimicrobial drugs, drug resistance, and the impact of antimicrobial therapy on public health. The journal publishes original research articles, reviews, and clinical studies, providing valuable insights into the field of antimicrobial agents and chemotherapy.
Details
Details
Abbr.
Antimicrob Agents Chemother
Publisher
American Society for Microbiology
Start
1972
End
Continuing
Frequency
Monthly
p-ISSN
0066-4804
e-ISSN
1098-6596
Country
United States
Language
English
Specialty
Pharmacology
Metrics
Metrics
h-index / Ranks: 233
289
SJR / Ranks: 2297
1357
CiteScore / Ranks: 1426
10.00
JIF / Ranks: 1632
4.9
Recent Articles
1.
Fighting resistance with redundancy: a path forward for treating antimicrobial-resistant infections?
Munita J, Tamma P
Antimicrob Agents Chemother
. 2025 Mar;
:e0012125.
PMID: 40084882
Carbapenem-resistant (CRAB) remains a major threat, with high mortality and limited effective treatments. Sulbactam-durlobactam has emerged as a promising therapy against CRAB. Sulbactam-durlobactam was combined with imipenem-cilastatin in a clinical...
2.
Petersen M, Khamas A, Ostergaard L, Jorgensen N, Meyer R
Antimicrob Agents Chemother
. 2025 Mar;
:e0148324.
PMID: 40084881
Antibiotic resistance, driven by misuse and overuse of antibiotics, is one of the greatest threats against human health. The antimicrobial pressure during prolonged antibiotic treatment of chronic bacterial infections selects...
3.
Huang Y, Chiaraviglio L, Bode-Sojobi I, Kirby J
Antimicrob Agents Chemother
. 2025 Mar;
:e0182824.
PMID: 40084880
Synergy of antimicrobial combinations was tested against contemporary isolates using 2D and 3D checkerboard assays. Triple combinations of omadacycline-azithromycin-clofazimine, tigecycline-azithromycin-clofazimine, omadacycline-azithromycin-linezolid, and omadacycline-azithromycin-contezolid demonstrated synergy (fractional inhibitory concentration index ≤...
4.
Rimal B, Howe R, Panthi C, Lamichhane G
Antimicrob Agents Chemother
. 2025 Mar;
:e0185324.
PMID: 40084879
a leading nontuberculous mycobacterium (NTM) pathogen, causes chronic pulmonary infections, particularly in individuals with underlying lung conditions or immunosuppression. Current treatments involve prolonged multidrug regimens with poor outcomes and significant...
5.
Ambati S, Choudhury Q, Peter J, Moremen K, Chapla D, Lewis Z, et al.
Antimicrob Agents Chemother
. 2025 Mar;
:e0172024.
PMID: 40084878
The sialic acid Ig-like lectins Siglec-3 and Siglec-15 are pathogen receptors that bind sialic acid-modified glycoproteins, best characterized in metastatic cancers. Because fungi produce sialoglycans and sialo-glycoproteins, we wondered if...
6.
Chen Y, Sun A, Narain K, Chang W, Yang C, Chen P, et al.
Antimicrob Agents Chemother
. 2025 Mar;
:e0159724.
PMID: 40079575
Febrile neutropenia (FN) is a serious complication in patients with hematologic malignancies following treatments such as chemotherapy and hematopoietic stem cell transplantation. It is typically managed with broad-spectrum antibiotics (BSA),...
7.
Ualiyeva S, McCallum J, Pyden A, Weiss Z
Antimicrob Agents Chemother
. 2025 Mar;
:e0186424.
PMID: 40071942
spp. are gram-positive bacteria increasingly recognized as pathogens. This study evaluates the MICs of omadacycline, a tetracycline, against 40 clinical isolates using two methodologies: broth microdilution (BMD) and Liofilchem omadacycline...
8.
Lombardi A, Pappas F, Bruinenberg P, Nedelman J, Taneja R, Hickman D, et al.
Antimicrob Agents Chemother
. 2025 Mar;
:e0154224.
PMID: 40067046
TBI-223 is an oxazolidinone antibiotic under clinical development for the treatment of tuberculosis. Preclinical data indicate potent antituberculosis activity and a potentially improved safety profile over linezolid. In a single-ascending...
9.
Sastre-Femenia M, Gomis-Font M, Oliver A
Antimicrob Agents Chemother
. 2025 Mar;
:e0194224.
PMID: 40067045
A growing number of novel antipseudomonal β-lactams have been introduced in recent years, but the emergence of resistance is still a major concern in the treatment of infections. Here, we...
10.
van der Veer M, Smits A, de Haan T, Franken L, van Kaam A, Hodiamont C, et al.
Antimicrob Agents Chemother
. 2025 Mar;
:e0111824.
PMID: 40067044
Amikacin is frequently used for the treatment of neonatal sepsis. The Dutch Pediatric Formulary recommends a complex pharmacokinetic (PK) model-derived dosing regimen, which consists of dosing categories based on postnatal...