Bruno Stieger
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Explore the profile of Bruno Stieger including associated specialties, affiliations and a list of published articles.
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Articles
164
Citations
4403
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Recent Articles
1.
Stieger B
Chimia (Aarau)
. 2023 Dec;
76(12):1025-1032.
PMID: 38069798
The liver fulfills many vital functions for the body, among them bile formation and detoxification. Bile salts are organic anions, are the major constituents of bile and are at high...
2.
van Rosmalen B, Visentin M, Furumaya A, van Delden O, Kazemier G, van Gulik T, et al.
Drug Metab Dispos
. 2023 Dec;
52(2):118-125.
PMID: 38050024
The organic anion uptake and efflux transporters [organic anion-transporting polypeptide (OATP)1B1, OATP1B3 and multidrug resistance-associated protein (MRP)2 and MRP3] that mediate the transport of the hepatobiliary-specific contrast agent gadoxetate (Gd-EOB-DTPA)...
3.
Liu H, Irobalieva R, Kowal J, Ni D, Nosol K, Bang-Sorensen R, et al.
Nat Commun
. 2023 Nov;
14(1):7296.
PMID: 37949847
BSEP (ABCB11) is an ATP-binding cassette transporter that is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. BSEP dysfunction, caused by mutations or induced by...
4.
Ciuta A, Nosol K, Kowal J, Mukherjee S, Ramirez A, Stieger B, et al.
Nat Commun
. 2023 Sep;
14(1):5774.
PMID: 37723174
The organic anion transporting polypeptides OATP1B1 and OATP1B3 are membrane proteins that mediate uptake of drugs into the liver for subsequent conjugation and biliary excretion, a key step in drug...
5.
Grossenbacher P, Essers M, Moser J, Singer S, Hausler S, Stieger B, et al.
RSC Adv
. 2022 Nov;
12(44):28306-28317.
PMID: 36320493
Antibodies are immensely useful tools for biochemical research and have found application in numerous protein detection and purification methods. Moreover, monoclonal antibodies are increasingly utilised as therapeutics or, conjugated to...
6.
Bakos E, Nemet O, Kucsma N, Tokesi N, Stieger B, Rushing E, et al.
Front Pharmacol
. 2022 Sep;
13:958023.
PMID: 36120371
Organic anion transporting polypeptide 3A1 (OATP3A1, encoded by the gene) is a prostaglandin, oligopeptide, and steroid/thyroid hormone transporter with wide tissue distribution, expressed, e.g., in the human brain and testis....
7.
Liu H, Irobalieva R, Bang-Sorensen R, Nosol K, Mukherjee S, Agrawal P, et al.
Cell Res
. 2022 Jun;
32(8):773-776.
PMID: 35726088
No abstract available.
8.
Luscher B, Albrecht C, Stieger B, Surbek D, Baumann M
Cells
. 2022 Feb;
11(4).
PMID: 35203284
Background: Hyperuricemia is a common laboratory finding in pregnant women compromised by preeclampsia. A growing body of evidence suggests that uric acid is involved in the pathogenesis of preeclampsia. Glucose...
9.
Nosol K, Bang-Sorensen R, Irobalieva R, Erramilli S, Stieger B, Kossiakoff A, et al.
Proc Natl Acad Sci U S A
. 2021 Aug;
118(33).
PMID: 34385322
ABCB4 is expressed in hepatocytes and translocates phosphatidylcholine into bile canaliculi. The mechanism of specific lipid recruitment from the canalicular membrane, which is essential to mitigate the cytotoxicity of bile...
10.
Impact on Bile Acid Concentrations by Alveolar Echinococcosis and Treatment with Albendazole in Mice
Gomez C, Jebbawi F, Weingartner M, Wang J, Stucheli S, Stieger B, et al.
Metabolites
. 2021 Aug;
11(7).
PMID: 34357336
Alveolar echinococcosis (AE) caused by is a chronic, progressive liver disease widely distributed in the Northern Hemisphere. The main treatment options include surgical interventions and chemotherapy with benzimidazole albendazole (ABZ)....