Stephane J C Mancini
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Explore the profile of Stephane J C Mancini including associated specialties, affiliations and a list of published articles.
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33
Citations
799
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Recent Articles
1.
Rondeau V, Kalogeraki M, Roland L, Nader Z, Gourhand V, Bonaud A, et al.
Sci Signal
. 2024 Oct;
17(860):eadl5100.
PMID: 39471249
Both cell-intrinsic and niche-derived, cell-extrinsic cues drive the specification of hematopoietic multipotent progenitors (MPPs) in the bone marrow, which comprise multipotent MPP1 cells and lineage-restricted MPP2, MPP3, and MPP4 subsets....
2.
Touarin P, Serrano B, Courbois A, Bornet O, Chen Q, Scott L, et al.
Cell Rep
. 2024 Jul;
43(8):114541.
PMID: 39058594
Galectins are glycan-binding proteins translating the sugar-encoded information of cellular glycoconjugates into physiological activities, including immunity, cell migration, and signaling. Galectins also interact with non-glycosylated partners in the extracellular milieu,...
3.
Grenier J, Testut C, Bal M, Bardin F, De Grandis M, Gelsi-Boyer V, et al.
Blood Adv
. 2024 Jul;
8(17):4662-4678.
PMID: 38954834
The leukemic stem cell (LSC) score LSC-17 based on a stemness-related gene expression signature is an indicator of poor disease outcome in acute myeloid leukemia (AML). However, it is not...
4.
Fregona V, Bayet M, Bouttier M, Largeaud L, Hamelle C, Jamrog L, et al.
J Exp Med
. 2023 Nov;
221(1).
PMID: 37930337
B cell acute lymphoblastic leukemia (B-ALL) is a multistep disease characterized by the hierarchical acquisition of genetic alterations. However, the question of how a primary oncogene reprograms stem cell-like properties...
5.
Anginot A, Nguyen J, Nader Z, Rondeau V, Bonaud A, Kalogeraki M, et al.
Nat Commun
. 2023 Apr;
14(1):2058.
PMID: 37045841
WHIM Syndrome is a rare immunodeficiency caused by gain-of-function CXCR4 mutations. Here we report a decrease in bone mineral density in 25% of WHIM patients and bone defects leading to...
6.
Pelletier J, Balzano M, Destin J, Montersino C, Delahaye M, Marchand T, et al.
iScience
. 2023 Apr;
26(4):106385.
PMID: 37009219
B-cell acute lymphoblastic leukemia (B-ALL) reflects the malignant counterpart of developing B cells in the bone marrow (BM). Despite tremendous progress in B-ALL treatment, the overall survival of adults at...
7.
Dumontet E, Mancini S, Tarte K
Front Immunol
. 2021 Dec;
12:784691.
PMID: 34956214
B-cell non-Hodgkin lymphoma (B-NHL) evolution and treatment are complicated by a high prevalence of relapses primarily due to the ability of malignant B cells to interact with tumor-supportive lymph node...
8.
Grenier J, Testut C, Fauriat C, Mancini S, Aurrand-Lions M
Front Immunol
. 2021 Dec;
12:756231.
PMID: 34867994
In the bone marrow (BM) of adult mammals, haematopoietic stem cells (HSCs) are retained in micro-anatomical structures by adhesion molecules that regulate HSC quiescence, proliferation and commitment. During decades, researchers...
9.
Mancini S, Balabanian K, Corre I, Gavard J, Lazennec G, Le Bousse-Kerdiles M, et al.
Front Immunol
. 2021 Dec;
12:766275.
PMID: 34858421
Knowledge about the hematopoietic niche has evolved considerably in recent years, in particular through analyzes, mouse models and the use of xenografts. Its complexity in the human bone marrow, in...
10.
Grenier J, Delahaye M, Mancini S, Aurrand-Lions M
Methods Mol Biol
. 2021 May;
2308:73-81.
PMID: 34057715
Flow cytometry has been widely used to detect a single event by means of multiparametric fluorescence measurements. Here we describe a method to analyze subsets of hematopoietic stem and progenitor...