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Stephane J C Mancini

Explore the profile of Stephane J C Mancini including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 799
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Recent Articles
11.
Delahaye M, Salem K, Pelletier J, Aurrand-Lions M, Mancini S
Front Oncol . 2021 Jan; 10:606540. PMID: 33489914
B-cell acute lymphoblastic leukemia (B-ALL) represents the malignant counterpart of bone marrow (BM) differentiating B cells and occurs most frequently in children. While new combinations of chemotherapeutic agents have dramatically...
12.
Bailly A, Grenier J, Cartier-Michaud A, Bardin F, Balzano M, Goubard A, et al.
J Immunol . 2020 Apr; 204(10):2685-2696. PMID: 32229537
Grasp55 is a ubiquitous Golgi stacking protein involved in autophagy, protein trafficking, and glucose deprivation sensing. The function of Grasp55 in protein trafficking has been attributed to its PDZ-mediated interaction...
13.
Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al.
Cell Rep . 2019 Mar; 26(12):3257-3271.e8. PMID: 30893599
In the bone marrow, CXCL12 and IL-7 are essential for B cell differentiation, whereas hematopoietic stem cell (HSC) maintenance requires SCF and CXCL12. Peri-sinusoidal stromal (PSS) cells are the main...
14.
Zidi B, Vincent-Fabert C, Pouyet L, Seillier M, Vandevelde A, Nguessan P, et al.
Proc Natl Acad Sci U S A . 2018 Dec; 116(1):211-216. PMID: 30559202
Bone marrow (BM) produces all blood and immune cells deriving from hematopoietic stem cells (HSCs). The decrease of immune cell production during aging is one of the features of immunosenescence....
15.
De Grandis M, Mancini S, Vey N, Aurrand-Lions M
Cancer Res . 2018 Oct; 78(21):6342-6343. PMID: 30333117
No abstract available.
16.
Jamrog L, Chemin G, Fregona V, Coster L, Pasquet M, Oudinet C, et al.
Proc Natl Acad Sci U S A . 2018 Sep; 115(41):10357-10362. PMID: 30257940
is a well-known haploinsufficient tumor suppressor gene in human B-cell precursor acute lymphoblastic leukemia (B-ALL) and is involved in various chromosomal translocations that fuse a part of PAX5 with other...
17.
Cresson C, Peron S, Jamrog L, Rouquie N, Prade N, Dubois M, et al.
Oncotarget . 2018 Sep; 9(67):32841-32854. PMID: 30214688
Pax5 is the guardian of the B cell identity since it primes or enhances the expression of B cell specific genes and concomitantly represses the expression of B cell inappropriate...
18.
Aurrand-Lions M, Mancini S
Int J Mol Sci . 2018 Aug; 19(8). PMID: 30103411
After birth, the development of hematopoietic cells occurs in the bone marrow. Hematopoietic differentiation is finely tuned by cell-intrinsic mechanisms and lineage-specific transcription factors. However, it is now clear that...
19.
De Grandis M, Bardin F, Fauriat C, Zemmour C, El-Kaoutari A, Serge A, et al.
Cancer Res . 2017 Oct; 77(23):6627-6640. PMID: 28972073
Acute myeloid leukemia (AML) originates from hematopoietic stem and progenitor cells that acquire somatic mutations, leading to disease and clonogenic evolution. AML is characterized by accumulation of immature myeloid cells...
20.
De Grandis M, Lhoumeau A, Mancini S, Aurrand-Lions M
Cell Mol Life Sci . 2015 Oct; 73(4):687-703. PMID: 26495446
Hematopoiesis takes place in the bone marrow of adult mammals and is the process by which blood cells are replenished every day throughout life. Differentiation of hematopoietic cells occurs in...