Science Signaling
Overview
Science Signaling is a peer-reviewed journal that focuses on the dynamic field of cellular signaling, providing comprehensive coverage of research on the molecular mechanisms underlying cell communication and signal transduction. It features original research articles, reviews, and perspectives, offering valuable insights into the intricate signaling networks that regulate various biological processes and their implications in health and disease.
Details
Details
Abbr.
Sci Signal
Start
2008
End
Continuing
Frequency
Weekly
p-ISSN
1945-0877
e-ISSN
1937-9145
Country
United States
Language
English
Specialties
Cell Biology
Physiology
Science
Physiology
Science
Metrics
Metrics
h-index / Ranks: 904
182
SJR / Ranks: 919
2341
CiteScore / Ranks: 868
12.50
JIF / Ranks: 805
7.3
Recent Articles
1.
Alonso-Maranon J, Sole L, Alvarez-Villanueva D, Maqueda M, Lobo-Jarne T, Montoto A, et al.
Sci Signal
. 2025 Mar;
18(877):eadr0128.
PMID: 40067909
The DNA damage repair kinase ATM is phosphorylated by the NF-κB pathway kinase IKKα, resulting in enhanced DNA damage repair through the nonhomologous end-joining pathway. Thus, inhibition of IKKα enhances...
2.
Wang W, Liang J, Zhang Y, Wang J, Miao X, Chang Y, et al.
Sci Signal
. 2025 Mar;
18(877):eadl6441.
PMID: 40067908
Brown and beige adipocytes dissipate energy to generate heat through uncoupled respiration, and the hormone norepinephrine plays an important role in stimulating brown fat thermogenesis and beige adipocyte development in...
3.
Wong W
Sci Signal
. 2025 Mar;
18(877):eadx2289.
PMID: 40067907
A mechanosensitive ion channel in a sensory neuron population suppresses the function of thermogenic tissues.
4.
Perkins N
Sci Signal
. 2025 Mar;
18(877):eadv1265.
PMID: 40067906
The kinase IKKα phosphorylates the kinase ATM, enhancing its ability to promote DNA repair. In this issue of , Alonso-Marañón demonstrate that in colorectal cancer cells, the IKK regulatory subunit...
5.
Baek A
Sci Signal
. 2025 Mar;
18(876):eadx0607.
PMID: 40036357
Peptidergic nociceptors promote gastric cancer through the release of the neuropeptide CGRP.
6.
Cho D, Han J, Kim I, Lim J, Ko H, Kim B, et al.
Sci Signal
. 2025 Mar;
18(876):eadp8973.
PMID: 40036356
Neuroinflammation promotes the progression of various neurological and neurodegenerative diseases. Disrupted homeostasis of protein acetylation is implicated in neurodegeneration, and the lysine acetyltransferase GCN5 (also known as KAT2A) is implicated...
7.
VanHook A
Sci Signal
. 2025 Feb;
18(875):eadw8586.
PMID: 39999213
A gut microbe that is reduced in diabetes produces a metabolite that dulls the appetite for sugar.
8.
Schwartz H, Sternberg P
Sci Signal
. 2025 Feb;
18(875):eadp9377.
PMID: 39999212
Suppressor screens can identify genetic modifiers of biochemical pathways but generally require that the suppressed mutant be viable and fertile. We developed a screening method that obviated this requirement and...
9.
Sona C, Yeh Y, Li Y, Liu X, Ghosh A, Hinte L, et al.
Sci Signal
. 2025 Feb;
18(875):eadl6745.
PMID: 39999211
Proper formation of the complex neurovascular unit (NVU) along with the blood-brain barrier is critical for building and sustaining a healthy, functioning central nervous system. The RNA binding protein argonaute2...
10.
Foley J
Sci Signal
. 2025 Feb;
18(873):eadw5249.
PMID: 39933020
A proximity assay identifies putative interactors and regulators of endogenous GPCRs in cell membranes.