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Somnath Dutta

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Articles 51
Citations 1222
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Recent Articles
1.
Harris S, Dutta S, Liu N, Wollenberg T, Wang X
Bioorg Med Chem Lett . 2024 Oct; 115:130008. PMID: 39481690
Antimicrobial resistance (AMR) is a formidable global health challenge. Multidrug-resistant (MDR) Gram-negative bacterial infections are of primary concern due to diminishing treatment options and high morbidity and mortality. Colistin, a...
2.
Garg P, Satheesh T, Ganji M, Dutta S
J Mol Biol . 2024 Sep; 436(21):168806. PMID: 39349276
DNA binding protein from starved cells (Dps) is a miniature ferritin complex, which plays a vital role in protecting bacterial DNA during starvation to maintain the integrity of bacteria under...
3.
Sarkar D, Khan A, Polepalli S, Sarkar R, Das P, Dutta S, et al.
Small . 2024 Jul; 20(45):e2404373. PMID: 39011730
Short peptide-based supramolecular hydrogels hold enormous potential for a wide range of applications. However, the gelation of these systems is very challenging to control. Minor changes in the peptide sequence...
4.
Dutta S, Eyolfson S, Zhu Y, Gao Y, Wang X
Org Biomol Chem . 2024 May; 22(20):4057-4061. PMID: 38716633
An efficient and practical one-pot synthesis of isoindolines from readily available starting materials was achieved under mild conditions by implementing an isoindole umpolung strategy. A variety of isoindolines were prepared...
5.
Shukla A, Banerjee M, Singh A, Penmatsa A, Dutta S, Anand R, et al.
Structure . 2024 Feb; 32(2):113-119. PMID: 38306986
To celebrate the 50th anniversary of Cell Press and the Cell special issue focusing on structural biology, we want to highlight the rapid progress of cryo-EM related research in India...
6.
Kumar S, Singh S, Chatterjee A, Bajpai P, Sharma S, Katpara S, et al.
iScience . 2023 Oct; 26(10):108013. PMID: 37854686
[This corrects the article DOI: 10.1016/j.isci.2023.107579.].
7.
Kumar S, Singh S, Chatterjee A, Bajpai P, Sharma S, Katpara S, et al.
iScience . 2023 Aug; 26(9):107579. PMID: 37649696
The structural and characteristic features of HIV-1 broadly neutralizing antibodies (bnAbs) from chronically infected pediatric donors are currently unknown. Herein, we characterized a heavy chain matured HIV-1 bnAb 44m, identified...
8.
Mishra S, Roy A, Dutta S
Structure . 2023 Apr; 31(6):651-667.e5. PMID: 37019111
γ-Hemolysin (γ-HL) is a hemolytic and leukotoxic bicomponent β-pore-forming toxin (β-PFT), a potent virulence factor from the Staphylococcus aureus Newman strain. In this study, we performed single-particle cryoelectron microscopy (cryo-EM)...
9.
Sengupta N, Padmanaban S, Dutta S
J Biol Chem . 2023 Mar; 299(4):104589. PMID: 36889587
Mycobacterium tuberculosis (Mtb) utilizes sophisticated machinery called the type VII secretion system to translocate virulence factors across its complex lipid membrane. EspB, a ∼36 kDa secreted substrate of the ESX-1...
10.
Khaleeq S, Sengupta N, Kumar S, Patel U, Rajmani R, Reddy P, et al.
Viruses . 2023 Feb; 15(2). PMID: 36851560
Rapid emergence of the SARS-CoV-2 variants has dampened the protective efficacy of existing authorized vaccines. Nanoparticle platforms offer a means to improve vaccine immunogenicity by presenting multiple copies of desired...