Scott R Gilbertson
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Explore the profile of Scott R Gilbertson including associated specialties, affiliations and a list of published articles.
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46
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348
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Recent Articles
11.
Gilbertson S, Chen Y, Soto C, Yang Y, Rice K, Cunningham K, et al.
Bioorg Med Chem Lett
. 2018 Mar;
28(8):1381-1385.
PMID: 29555153
The approach of tethering together two known receptor ligands, to be used as molecular probes for the study of G protein-coupled receptor (GPCR) systems, has proven to be a valuable...
12.
Soto C, Shashack M, Fox R, Bubar M, Rice K, Watson C, et al.
ACS Chem Neurosci
. 2017 Nov;
9(3):514-521.
PMID: 29111677
The 5-HT receptor (5-HTR) plays an important role in various neuropsychiatric disorders, including substance use disorder and schizophrenia. Homodimerization of this receptor has been suggested, but tools that allow direct...
13.
Chen Y, Hartley R, Anastasio N, Cunningham K, Gilbertson S
ACS Chem Neurosci
. 2017 Apr;
8(5):1004-1010.
PMID: 28414422
The development of probe molecules that can be used to investigate G protein-coupled receptor (GPCR) pharmacology, trafficking, and relationship with other GPCRs is an important and growing area of research....
14.
Do H, Zhang N, Pati D, Gilbertson S
Bioorg Med Chem Lett
. 2016 Aug;
26(18):4446-4450.
PMID: 27530289
Due to the oncogenic activity of cohesin protease, separase in human cancer cells, modulation of separase enzymatic activity could constitute a new therapeutic strategy for targeting resistant, separase-overexpressing aneuploid tumors....
15.
Do H, Kang C, Cho J, Gilbertson S
Org Lett
. 2015 Aug;
17(16):3972-4.
PMID: 26258884
Dysiherbaine, a natural product isolated from the Marine sponge Dysidea herbacea, has been shown to be a selective agonist of non-NMDA type glutamate receptors, kainate receptors. An enantioselective synthesis of...
16.
Canlas G, Gilbertson S
Chem Commun (Camb)
. 2014 Apr;
50(39):5007-10.
PMID: 24706156
A rhodium-BozPHOS based complex is reported. This complex is competent in catalyzing the [4+2+2] cycloisomerization of cyclooctatrienes in moderate to good yields. The X-ray crystal structure of this complex is...
17.
Zhao Y, Gilbertson S
Org Lett
. 2014 Feb;
16(4):1033-5.
PMID: 24495075
The synthesis of proline-based N-heterocyclic carbene ligands is reported. An approach to a variety of proline-containing imidazolium NHC precursors is presented. The proline amino acids are shown to be compatible...
18.
De S, Chen L, Zhang S, Gilbertson S
ACS Comb Sci
. 2013 Jun;
15(7):340-3.
PMID: 23742807
Through the use of the dipolar cycloaddition of isomunchones with olefins the 2(1H)-pyridone ring system has been synthesized. (1) The use of different cyclization partners followed by diversification of the...
19.
Anastasio N, Gilbertson S, Bubar M, Agarkov A, Stutz S, Jeng Y, et al.
J Neurosci
. 2013 Jan;
33(4):1615-30.
PMID: 23345234
Serotonin (5-hydroxytryptamine; 5-HT) signaling through the 5-HT(2C) receptor (5-HT(2C)R) is essential in normal physiology, whereas aberrant 5-HT(2C)R function is thought to contribute to the pathogenesis of multiple neural disorders. The...
20.
Cunningham K, Anastasio N, Fox R, Stutz S, Bubar M, Swinford S, et al.
ACS Chem Neurosci
. 2013 Jan;
4(1):110-21.
PMID: 23336050
Relapse to cocaine dependence, even after extended abstinence, involves a number of liability factors including impulsivity (predisposition toward rapid, unplanned reactions to stimuli without regard to negative consequences) and cue...