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Noelle C Anastasio

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Citations 849
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Recent Articles
1.
Salinsky L, Merritt C, Garcia E, Fox R, Zamora J, Anastasio N, et al.
Psychopharmacology (Berl) . 2025 Mar; PMID: 40035828
Rationale And Objectives: Overdose fatalities involving cocaine continue to rise with over 5.3 million cocaine users reported in the United States in 2022. The abuse liability of cocaine is reliant...
2.
Salinsky L, Merritt C, Zamora J, Giacomini J, Anastasio N, Cunningham K
Front Pharmacol . 2023 Oct; 14:1239159. PMID: 37886127
Opioid misuse and opioid-involved overdose deaths are a massive public health problem involving the intertwined misuse of prescription opioids for pain management with the emergence of extremely potent fentanyl derivatives,...
3.
Merritt C, Garcia E, Brehm V, Fox R, Moeller F, Anastasio N, et al.
Front Pharmacol . 2023 Oct; 14:1268366. PMID: 37795028
The drug overdose crisis has spawned serious health consequences, including the increased incidence of substance use disorders (SUDs), conditions manifested by escalating medical and psychological impairments. While medication management is...
4.
Chen J, Garcia E, Merritt C, Zamora J, Bolinger A, Pazdrak K, et al.
J Med Chem . 2023 Jul; 66(14):9992-10009. PMID: 37462530
The serotonin 5-HT receptor (5-HTR) and 5-HTR localize to the brain and share overlapping signal transduction facets that contribute to their roles in cognition, mood, learning, and memory. Achieving selective...
5.
Merritt C, Smith A, Khanipov K, Golovko G, Dineley K, Anastasio N, et al.
Front Pharmacol . 2023 Jan; 13:1022863. PMID: 36588704
Drug overdose deaths involving cocaine have skyrocketed, an outcome attributable in part to the lack of FDA-approved medications for the treatment of cocaine use disorder (CUD), highlighting the need to...
6.
Ma L, Cunningham K, Anastasio N, Bjork J, Taylor B, Arias A, et al.
Transl Psychiatry . 2022 May; 12(1):187. PMID: 35523779
Cocaine use disorder (CUD) patients display heterogenous symptoms and unforeseeable responses to available treatment approaches, highlighting the need to identify objective, accessible biobehavioral signatures to predict clinical trial success in...
7.
Johns S, Keyser-Marcus L, Abbate A, Boone E, Van Tassell B, Cunningham K, et al.
Front Psychiatry . 2021 Jul; 12:666945. PMID: 34276440
Preclinical studies show serotonin (5-HT) 5-HT receptor (5-HTR) agonists reduce cocaine-seeking and cocaine intake. This study examined safety of the 5-HTR agonist lorcaserin administered with cocaine in participants with cocaine...
8.
Davis-Reyes B, Smith A, Xu J, Cunningham K, Zhou J, Anastasio N
Behav Pharmacol . 2021 Feb; 32(4):335-344. PMID: 33595955
The concept of 'impulse control' has its roots in early psychiatry and today has progressed into a well-described, although poorly understood, multidimensional endophenotype underlying many neuropsychiatric disorders (e.g., attention deficit...
9.
Nigam K, Straub L, Zuniga E, Sami A, Cunningham K, Anastasio N, et al.
Drug Alcohol Depend . 2020 Nov; 218:108402. PMID: 33243584
Background: Impulsivity is an established risk factor for substance use disorder (SUD). Integral to SUD recovery is proactive control (leveraging information about a potential need for behavioral restraint to marshal...
10.
Land M, Ramesh D, Miller A, Pyles R, Cunningham K, Moeller F, et al.
Front Psychiatry . 2020 Jun; 11:532. PMID: 32587535
Relapse during abstinence in cocaine use disorder (CUD) is often hastened by high impulsivity (predisposition toward rapid unplanned reactions to stimuli without regard to negative consequences) and high cue reactivity...