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The Journal of Organic Chemistry

The Journal of Organic Chemistry is a renowned scientific publication that focuses on the study of organic compounds and their properties, reactions, and synthesis. It covers a wide range of topics including organic synthesis, physical organic chemistry, bioorganic chemistry, and medicinal chemistry. With its rigorous peer-review process, the journal provides a platform for researchers to share their groundbreaking discoveries and advancements in the field of organic chemistry.

Details
Abbr. J Org Chem
Start 1936
End Continuing
Frequency Biweekly
p-ISSN 0022-3263
e-ISSN 1520-6904
Country United States
Language English
Specialty Chemistry
Metrics
h-index / Ranks: 400 244
SJR / Ranks: 6068 724
CiteScore / Ranks: 3060 6.80
JIF / Ranks: 2654 3.6
Recent Articles
1.
Yin Z, Zhang Q, Liu W, Niu C, Chen M, Wang G
J Org Chem . 2025 Mar; PMID: 40087024
Tether-directed electrosynthesis of [60]fullerene derivatives fused with 5-membered azacycle and 13-membered carbocycle, that is, bicyclic 1,4,9,12- and 1,2,4,15-adducts, has been achieved unexpectedly for the first time. The novel bicyclic [60]fullerene...
2.
El Gharbi M, Bianchi E, Coelho A, Kowandy C, Behr J, Vasse J
J Org Chem . 2025 Mar; PMID: 40085798
The synthesis of 2- and 6-substituted-3-aminopiperidines from Weinreb amides containing an allylamino fragment is reported. Involving the simultaneous hydrozirconation of the C═C and the C═O bonds, the cyclization was promoted...
3.
Li Y, Li S, Du H, Hao Y, Cheng Y, Liu X, et al.
J Org Chem . 2025 Mar; PMID: 40085740
An efficient Rh(III)-catalyzed annulation between 3-aryl-2-benzo[][1,4]oxazines and α-diazo-β-ketoesters was developed, affording a series of polycyclic heteroarenes in moderate to excellent yields with good functional group compatibility. The procedure featured high...
4.
Neal M, Chartier E, Lane A, Hejnosz S, Jesikiewicz L, Liu P, et al.
J Org Chem . 2025 Mar; 90(10):3673-3683. PMID: 40083234
The physical model used to compute natural phenomena is crucial for accurate structural and mechanism elucidation. Specifically, we examine the mechanistic consequences of an explicit LDA dimer, THF, and -oxide...
5.
Mishra K, Hendrix I, Gerardo J, Yamamoto N, Yan Y
J Org Chem . 2025 Mar; PMID: 40080873
Dual functionalization in organic synthesis represents a powerful strategy aimed at achieving multiple transformations within a single reaction cycle, thereby streamlining synthetic processes, enhancing efficiency, and imparting economic paths for...
6.
Jin Y, Fu J, Jiang C, Ding Z
J Org Chem . 2025 Mar; PMID: 40080862
Bicyclo[3.2.1]octanes widely exist in natural products and bioactive compounds. However, the efficient construction of these skeletons remains a challenge. Herein, we reported a convenient synthesis of diaza-oxabicyclo[3.2.1]octanes and dioxa-azabicyclo[3.2.1]octanes by...
7.
Tsybulin S, Meshalkin S, Tonkoglazova D, Bardakov V, Pozharskii A, Antonov A
J Org Chem . 2025 Mar; PMID: 40080825
Non-covalent interactions are a highly promising tool for the development of transition-metal-free chemospecific synthetic transformations. Here, we demonstrate the implementation of non-covalent interactions as a simple, precise, and flexible synthetic...
8.
Lu X, Huang A, Jia A, Tang S
J Org Chem . 2025 Mar; PMID: 40080443
The fascinating skeleton 3,2'-pyrrolidinyl spirooxindole exhibits diverse pharmacological activity. Despite advancements in the construction of this skeleton, the application rearrangement strategy for the synthesis of 3,2'-pyrrolidinyl spirooxindole remains underexplored. Herein,...
9.
Ramiro J, Diaz J, G Neo A, F Marcos C
J Org Chem . 2025 Mar; PMID: 40080150
The enol-Ugi condensation, a versatile multicomponent reaction, provides a rapid and efficient route to enamine peptidomimetics. In this study, we investigated the factors influencing the conformational behavior of three enol-Ugi...
10.
Gong Z, Smith A, Harrison C, Trapnell E, Wiskur S
J Org Chem . 2025 Mar; PMID: 40080082
A lone pair-π interaction was employed to alter the reactivity of three isochalcogenourea catalysts in a model silylation reaction. Even though a lone pair-π interaction is a relatively weak interaction,...