Sasmita Tripathy
Overview
Explore the profile of Sasmita Tripathy including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
962
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0
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Recent Articles
1.
Sager J, Tripathy S, Price L, Nath A, Chang J, Stephenson-Famy A, et al.
Biochem Pharmacol
. 2020 Nov;
183:114306.
PMID: 33161206
No abstract available.
2.
Jump D, Lytle K, Depner C, Tripathy S
Pharmacol Ther
. 2017 Jul;
181:108-125.
PMID: 28723414
Obese and type 2 diabetic (T2DM) patients have a high prevalence of nonalcoholic fatty liver disease (NAFLD). NAFLD is a continuum of chronic liver diseases ranging from benign hepatosteatosis to...
3.
Stevison F, Hogarth C, Tripathy S, Kent T, Isoherranen N
Drug Metab Dispos
. 2017 Apr;
45(7):846-854.
PMID: 28446509
retinoic acid (RA), the active metabolite of vitamin A, is a ligand for several nuclear receptors and acts as a critical regulator of many physiologic processes. The cytochrome P450 family...
4.
Sager J, Tripathy S, Price L, Nath A, Chang J, Stephenson-Famy A, et al.
Biochem Pharmacol
. 2016 Nov;
123:85-96.
PMID: 27836670
Bupropion is a widely used antidepressant and smoking cessation aid and a strong inhibitor of CYP2D6 in vivo. Bupropion is administered as a racemic mixture of R- and S-bupropion and...
5.
Tripathy S, Chapman J, Han C, Hogarth C, Arnold S, Onken J, et al.
Mol Pharmacol
. 2016 Feb;
89(5):560-74.
PMID: 26921399
All-trans-retinoic acid (atRA) is the active metabolite of vitamin A. The liver is the main storage organ of vitamin A, but activation of the retinoic acid receptors (RARs) in mouse...
6.
Diaz P, Huang W, Keyari C, Buttrick B, Price L, Guilloteau N, et al.
J Med Chem
. 2016 Feb;
59(6):2579-95.
PMID: 26918322
Cytochrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance. Inhibition of CYP26 enzymes will increase endogenous atRA concentrations and is an attractive therapeutic target. However, the selectivity and...
7.
Jump D, Depner C, Tripathy S, Lytle K
Adv Nutr
. 2015 Nov;
6(6):694-702.
PMID: 26567194
Nonalcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity, and its prevalence is anticipated to increase as the obesity epidemic remains unabated. NAFLD is now the most...
8.
Jump D, Depner C, Tripathy S, Lytle K
Proc Nutr Soc
. 2015 Aug;
75(1):1-9.
PMID: 26282529
The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity and is now the most common chronic liver disease in developed countries. NAFLD is defined...
9.
Stevison F, Jing J, Tripathy S, Isoherranen N
Adv Pharmacol
. 2015 Aug;
74:373-412.
PMID: 26233912
Vitamin A (retinol) and its active metabolite, all-trans-retinoic acid (atRA), play critical roles in regulating the differentiation, growth, and migration of immune cells. Similarly, as critical signaling molecules in the...
10.
Topletz A, Tripathy S, Foti R, Shimshoni J, Nelson W, Isoherranen N
Mol Pharmacol
. 2014 Dec;
87(3):430-41.
PMID: 25492813
All-trans-retinoic acid (atRA), the active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). The primary hydroxylated metabolites formed from atRA by CYP26A1, and...