Travis Kent
Overview
Explore the profile of Travis Kent including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
338
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Recent Articles
1.
Larose H, Kent T, Ma Q, Shami A, Harerimana N, Li J, et al.
Mol Biol Cell
. 2020 Oct;
31(25):2841-2862.
PMID: 33026960
Androgen receptor (AR) signaling in Sertoli cells is known to be important for germ-cell progression through meiosis, but the extent to which androgens indirectly regulate specific meiotic stages is not...
2.
Stevison F, Hogarth C, Tripathy S, Kent T, Isoherranen N
Drug Metab Dispos
. 2017 Apr;
45(7):846-854.
PMID: 28446509
retinoic acid (RA), the active metabolite of vitamin A, is a ligand for several nuclear receptors and acts as a critical regulator of many physiologic processes. The cytochrome P450 family...
3.
Tripathy S, Chapman J, Han C, Hogarth C, Arnold S, Onken J, et al.
Mol Pharmacol
. 2016 Feb;
89(5):560-74.
PMID: 26921399
All-trans-retinoic acid (atRA) is the active metabolite of vitamin A. The liver is the main storage organ of vitamin A, but activation of the retinoic acid receptors (RARs) in mouse...
4.
Kent T, Arnold S, Fasnacht R, Rowsey R, Mitchell D, Hogarth C, et al.
Biol Reprod
. 2015 Dec;
94(1):12.
PMID: 26632609
Perturbations in the vitamin A metabolism pathway could be a significant cause of male infertility, as well as a target toward the development of a male contraceptive, necessitating the need...
5.
Hogarth C, Evans E, Onken J, Kent T, Mitchell D, Petkovich M, et al.
Biol Reprod
. 2015 Jun;
93(1):19.
PMID: 26040672
The active metabolite of vitamin A, retinoic acid (RA), is known to be essential for spermatogenesis. Changes to RA levels within the seminiferous epithelium can alter the development of male...
6.
Arnold S, Kent T, Hogarth C, Griswold M, Amory J, Isoherranen N
Biochem Pharmacol
. 2015 Mar;
95(3):177-92.
PMID: 25764981
all-trans retinoic acid (atRA), the active metabolite of vitamin A, is an essential signaling molecule. Specifically the concentrations of atRA are spatiotemporally controlled in target tissues such as the liver...
7.
Hogarth C, Arnold S, Kent T, Mitchell D, Isoherranen N, Griswold M
Biol Reprod
. 2014 Dec;
92(2):37.
PMID: 25519186
The asynchronous cyclic nature of spermatogenesis is essential for continual sperm production and is one of the hallmarks of mammalian male fertility. While various mRNA and protein localization studies have...
8.
Arnold S, Kent T, Hogarth C, Schlatt S, Prasad B, Haenisch M, et al.
J Lipid Res
. 2014 Dec;
56(2):342-57.
PMID: 25502770
Retinoic acid (RA), the active metabolite of vitamin A, is required for spermatogenesis and many other biological processes. RA formation requires irreversible oxidation of retinal to RA by aldehyde dehydrogenase...
9.
Hogarth C, Evanoff R, Mitchell D, Kent T, Small C, Amory J, et al.
Biol Reprod
. 2013 Jan;
88(2):40.
PMID: 23284139
The BDADs (bis-[dichloroacetyl]-diamines) are compounds that can inhibit spermatogenesis via blocking the metabolism of vitamin A. We utilized one specific BDAD, WIN 18,446, to manipulate the endogenous production of retinoic...
10.
Hogarth C, Evanoff R, Snyder E, Kent T, Mitchell D, Small C, et al.
Biol Reprod
. 2011 Jan;
84(5):957-65.
PMID: 21209416
Bis-(dichloroacetyl)-diamines (BDADs) are compounds that inhibit spermatogenesis and function as male contraceptives in many species; however, their mechanism of action has yet to be fully investigated. It has been proposed...