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Rachel Finck

Explore the profile of Rachel Finck including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 4059
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Recent Articles
1.
Ptacek J, Locke D, Finck R, Cvijic M, Li Z, Tarolli J, et al.
Lab Invest . 2020 Mar; 100(8):1111-1123. PMID: 32203152
An ability to characterize the cellular composition and spatial organization of the tumor microenvironment (TME) using multiplexed IHC has been limited by the techniques available. Here we show the applicability...
2.
Behbehani G, Finck R, Samusik N, Sridhar K, Fantl W, Greenberg P, et al.
Cytometry B Clin Cytom . 2020 Jan; 98(2):131-145. PMID: 31917512
Background: We sought to enhance the cytometric analysis of myelodysplastic syndromes (MDS) by performing a pilot study of a single cell mass cytometry (MCM) assay to more comprehensively analyze patterns...
3.
Finck R, Ziman A, Hoffman M, Phan-Tang M, Yuan S
J Blood Transfus . 2016 Jun; 2016:8624230. PMID: 27293985
Background. To ensure an adequate supply of blood, collection centers must design campaigns that successfully recruit and maintain an active donor pool. Understanding factors that motivate and deter individuals from...
4.
Hotson A, Gopinath S, Nicolau M, Khasanova A, Finck R, Monack D, et al.
Sci Signal . 2016 Jan; 9(410):ra4. PMID: 26758212
The immune system enacts a coordinated response when faced with complex environmental and pathogenic perturbations. We used the heterogeneous responses of mice to persistent Salmonella infection to model system-wide coordination...
5.
Spitzer M, Gherardini P, Fragiadakis G, Bhattacharya N, Yuan R, Hotson A, et al.
Science . 2015 Jul; 349(6244):1259425. PMID: 26160952
Immune cells function in an interacting hierarchy that coordinates the activities of various cell types according to genetic and environmental contexts. We developed graphical approaches to construct an extensible immune...
6.
Levine J, Simonds E, Bendall S, Davis K, Amir E, Tadmor M, et al.
Cell . 2015 Jun; 162(1):184-97. PMID: 26095251
Acute myeloid leukemia (AML) manifests as phenotypically and functionally diverse cells, often within the same patient. Intratumor phenotypic and functional heterogeneity have been linked primarily by physical sorting experiments, which...
7.
Zunder E, Finck R, Behbehani G, Amir E, Krishnaswamy S, Gonzalez V, et al.
Nat Protoc . 2015 Jan; 10(2):316-33. PMID: 25612231
Mass-tag cell barcoding (MCB) labels individual cell samples with unique combinatorial barcodes, after which they are pooled for processing and measurement as a single multiplexed sample. The MCB method eliminates...
8.
Behbehani G, Thom C, Zunder E, Finck R, Gaudilliere B, Fragiadakis G, et al.
Cytometry A . 2014 Oct; 85(12):1011-9. PMID: 25274027
Fluorescent cellular barcoding and mass-tag cellular barcoding are cytometric methods that enable high sample throughput, minimize inter-sample variation, and reduce reagent consumption. Previously employed barcoding protocols require that barcoding be...
9.
Gaudilliere B, Fragiadakis G, Bruggner R, Nicolau M, Finck R, Tingle M, et al.
Sci Transl Med . 2014 Sep; 6(255):255ra131. PMID: 25253674
Delayed recovery from surgery causes personal suffering and substantial societal and economic costs. Whether immune mechanisms determine recovery after surgical trauma remains ill-defined. Single-cell mass cytometry was applied to serial...
10.
Angelo M, Bendall S, Finck R, Hale M, Hitzman C, Borowsky A, et al.
Nat Med . 2014 Mar; 20(4):436-42. PMID: 24584119
Immunohistochemistry (IHC) is a tool for visualizing protein expression that is employed as part of the diagnostic workup for the majority of solid tissue malignancies. Existing IHC methods use antibodies...