Sean C Bendall
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Explore the profile of Sean C Bendall including associated specialties, affiliations and a list of published articles.
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109
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10567
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Recent Articles
1.
Liu Y, Jiang H, Liu J, Stuani L, Merchant M, Jager A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975156
Relapse continues to limit survival for patients with B-cell acute lymphoblastic leukemia (B-ALL). Previous studies have independently implicated activation of B-cell developmental signaling pathways and increased glucose consumption with chemo-resistance...
2.
Kim Y, Calderon A, Favaro P, Glass D, Tsai A, Ho D, et al.
Nat Commun
. 2024 Jul;
15(1):5910.
PMID: 39003273
Lymphoid specification in human hematopoietic progenitors is not fully understood. To better associate lymphoid identity with protein-level cell features, we conduct a highly multiplexed single-cell proteomic screen on human bone...
3.
Dellorusso P, Proven M, Calero-Nieto F, Wang X, Mitchell C, Hartmann F, et al.
Cell Stem Cell
. 2024 May;
31(7):1020-1037.e9.
PMID: 38754428
Autophagy is central to the benefits of longevity signaling programs and to hematopoietic stem cell (HSC) response to nutrient stress. With age, a subset of HSCs increases autophagy flux and...
4.
Yakabi K, Berson E, Montine K, Bendall S, MacCoss M, Poston K, et al.
bioRxiv
. 2024 Jan;
PMID: 38187636
Exosomes are proposed to be important in the pathogenesis of prevalent neurodegenerative diseases. We report the first application of solid-state technology to perform multiplex analysis of single exosomes in human...
5.
Karacosta L, Pancirer D, Preiss J, Benson J, Trope W, Shrager J, et al.
Sci Rep
. 2023 Dec;
13(1):21781.
PMID: 38065965
Malignant pleural effusions (MPEs) can be utilized as liquid biopsy for phenotyping malignant cells and for precision immunotherapy, yet MPEs are inadequately studied at the single-cell proteomic level. Here we...
6.
Adamik J, Munson P, Maurer D, Hartmann F, Bendall S, Arguello R, et al.
Nat Commun
. 2023 Nov;
14(1):7211.
PMID: 37938561
Efficacy of cancer vaccines remains low and mechanistic understanding of antigen presenting cell function in cancer may improve vaccine design and outcomes. Here, we analyze the transcriptomic and immune-metabolic profiles...
7.
Favaro P, Glass D, Borges L, Baskar R, Reynolds W, Ho D, et al.
bioRxiv
. 2023 Sep;
PMID: 37693547
Hematopoietic stem and progenitor cell (HSPC) transplantation is an essential therapy for hematological conditions, but finer definitions of human HSPC subsets with associated function could enable better tuning of grafts...
8.
Dellorusso P, Proven M, Calero-Nieto F, Wang X, Mitchell C, Hartmann F, et al.
bioRxiv
. 2023 Aug;
PMID: 37645930
One-sentence Summary: Autophagy compensates for chronic inflammation-induced metabolic deregulation in old HSCs, and its transient modulation can reset old HSC glycolytic and regenerative capacity.
9.
Berson E, Gajera C, Phongpreecha T, Perna A, Bukhari S, Becker M, et al.
Sci Rep
. 2023 Aug;
13(1):13849.
PMID: 37620363
Comparing brain structure across species and regions enables key functional insights. Leveraging publicly available data from a novel mass cytometry-based method, synaptometry by time of flight (SynTOF), we applied an...
10.
Rao M, Amouzgar M, Harden J, Lapasaran M, Trickey A, Armstrong B, et al.
Cell Rep Med
. 2023 Aug;
4(8):101147.
PMID: 37552988
Solid organ transplant remains a life-saving therapy for children with end-stage heart, lung, liver, or kidney disease; however, ∼33% of allograft recipients experience acute rejection within the first year after...