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Laboratory Investigation; a Journal of Technical Methods and Pathology

Laboratory Investigation is a renowned journal that focuses on technical methods and pathology. It provides a platform for scientists, researchers, and pathologists to publish their cutting-edge findings and advancements in laboratory techniques. With a strong emphasis on rigorous investigation, this journal serves as a valuable resource for professionals seeking to deepen their understanding of various laboratory methodologies and their applications in the field of pathology.

Details
Abbr. Lab Invest
Start 1952
End Continuing
Frequency Monthly, <June 2005->
p-ISSN 0023-6837
e-ISSN 1530-0307
Country United States
Language English
Specialty Pathology
Metrics
h-index / Ranks: 1149 166
SJR / Ranks: 2683 1243
CiteScore / Ranks: 2159 8.20
JIF / Ranks: 1573 5.0
Recent Articles
1.
Gotlieb A, Mitchell R
Lab Invest . 2025 Mar; :104126. PMID: 40086697
No abstract available.
2.
Yang S, Hu T, Ching-Wu J, Yi L, Kuo H, Kung M, et al.
Lab Invest . 2025 Mar; :104127. PMID: 40081662
Hepatoma-derived growth factor (HDGF) is located on chromosome 1q21-23, a locus frequently amplified in hepatocellular carcinoma (HCC), and has been proposed as an oncogenic factor by stimulating PI3K/Akt signaling. Phosphatase...
3.
Radner M, Burmeister S, Jozwiak K, Schaumann N, Gronewold M, Raap M, et al.
Lab Invest . 2025 Mar; :104125. PMID: 40049332
Background: Invasive lobular carcinoma with tubular elements (ILC-TE) is a recently identified variant of invasive lobular breast carcinoma (ILC). The histology of ILC-TE is defined by non-cohesive carcinoma cells mixed...
4.
Seok J, Kwak H, Kang C, Kim A, Choi W, Park H, et al.
Lab Invest . 2025 Mar; :104124. PMID: 40043910
Bladder cancer (BCa) is the most common malignancy of the urinary system with high incidence and recurrence rates. There are several ways to detect BCa. However, different approaches have different...
5.
Fang R, Vallius T, Zhang A, Van Cura D, Alicandri F, Fischer G, et al.
Lab Invest . 2025 Mar; :104123. PMID: 40024557
Preferentially Expressed Antigen in Melanoma (PRAME) and Ten-Eleven Translocation (TET) dioxygenase-mediated 5-hydroxymethylcytosine (5hmC) are emerging melanoma biomarkers. We observed an inverse correlation between PRAME expression and 5hmC levels in benign...
6.
Xu T, Bassiouny D, Srinidhi C, Lam M, Goubran M, Nofech-Mozes S, et al.
Lab Invest . 2025 Feb; :104121. PMID: 40020876
Lymph node assessment for metastasis is a common, time-consuming, and potentially error prone pathologist task. Past studies have proposed deep learning (DL) algorithms designed to automate this task. However, none...
7.
Li Y, Fan S, Xia W, Qiao B, Huang K, Zhou J, et al.
Lab Invest . 2025 Feb; 105(4):104108. PMID: 40014979
No abstract available.
8.
Ricciardi G, Fiorentino V, Pierconti F, Giordano W, Giordano W, Germana E, et al.
Lab Invest . 2025 Feb; 105(5):104120. PMID: 40010639
In this retrospective observational multicenter study, we identified tumors and immune markers that are related to each other, which could help in selecting patients with bladder primary urothelial carcinoma in...
9.
Cabello-Aguilar S, Vendrell J, Evrard S, Thomas Q, Roch B, Escudie F, et al.
Lab Invest . 2025 Feb; :104117. PMID: 39986540
MET amplification (MET) is a noteworthy genomic alteration that can occur in patients with non-small cell lung cancer (NSCLC). It has been demonstrated to occur as a primary oncogenic driver...
10.
Mechahougui H, Hildebrand L, Haberberger J, Sivakumar S, Saiji E, Tukachinsky H, et al.
Lab Invest . 2025 Feb; 105(5):104116. PMID: 39984125
Treatment for gastrointestinal stromal tumor (GIST) focuses on tyrosine kinase inhibitors, the selection of which depends on specific mutations. We sought to determine the clinical use of liquid biopsy in...