Pieter Van der Veken
Overview
Explore the profile of Pieter Van der Veken including associated specialties, affiliations and a list of published articles.
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140
Citations
1574
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Recent Articles
1.
Van Elzen R, Waumans Y, Nath S, Van der Veken P, Kerckhoff S, Van Dijk E, et al.
Biochimie
. 2025 Feb;
PMID: 39984111
The aim of this work was to revisit the connection between prolyl oligopeptidase (PREP) and α-synuclein (aSyn) by presenting novel data from cell free and cellular assays and to discuss...
2.
Scarpellini C, Klejborowska G, Lanthier C, Toye A, Musialek K, Van San E, et al.
J Med Chem
. 2025 Feb;
68(4):4908-4928.
PMID: 39913870
Ferroptosis plays an important role in the occurrence and development of many diseases, including neurodegenerative diseases. Thus, ferroptosis inhibitors able to cross the blood-brain barrier may have therapeutic potential. The...
3.
Beyens O, Corthaut S, Lambeir A, Van der Veken P, Sterckx Y, De Meester I, et al.
ChemMedChem
. 2024 Nov;
20(5):e202400700.
PMID: 39552560
Dipeptidyl peptidase 8 (DPP8) and 9 (DPP9) are proteases gaining significant attention for their role in health and disease. Distinctive studies of these proteases are hampered by their close homology....
4.
Beyens O, Corthaut S, Peeters S, Van der Veken P, De Meester I, De Winter H
J Chem Inf Model
. 2024 Sep;
64(19):7650-7665.
PMID: 39332821
We present our efforts in computational drug design against dipeptidyl peptidase 4 (DPP4), DPP8 and DPP9. We applied cosolvent molecular dynamics (MD) simulations to these three protein targets of interest....
5.
Lauwerys L, Beroske L, Solania A, Vangestel C, Miranda A, Van Giel N, et al.
EJNMMI Radiopharm Chem
. 2024 Aug;
9(1):58.
PMID: 39117920
Background: The cysteine-aspartic acid protease caspase-3 is recognized as the main executioner of apoptosis in cells responding to specific extrinsic and intrinsic stimuli. Caspase-3 represents an interesting biomarker to evaluate...
6.
Ke B, Abdurahiman S, Biscu F, Zanella G, Dragoni G, Santhosh S, et al.
J Clin Invest
. 2024 Jul;
134(16).
PMID: 39042469
Crohn's disease (CD) is marked by recurring intestinal inflammation and tissue injury, often resulting in fibrostenosis and bowel obstruction, necessitating surgical intervention with high recurrence rates. To elucidate the mechanisms...
7.
Van Elzen R, Konijnenberg A, Van der Veken P, Edgeworth M, Scrivens J, Fulop V, et al.
J Med Chem
. 2024 May;
67(12):10436-10446.
PMID: 38783480
Ion mobility mass spectrometry (IM-MS) can be used to analyze native proteins according to their size and shape. By sampling individual molecules, it allows us to study mixtures of conformations,...
8.
Bozdag M, Mertens F, Matheeussen A, Van Pelt N, Foubert K, Hermans N, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731916
Herein, we report a series of 1,3-diarylpyrazoles that are analogues of compound /HIT 8. We previously identified this molecule as a 'hit' during a high-throughput screening campaign for autophagy inducers....
9.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, et al.
J Med Chem
. 2024 Apr;
67(9):7068-7087.
PMID: 38656144
Fibroblast activation protein (FAP) is a very reliable biomarker for tissue remodeling. FAP has so far mainly been studied in oncology, but there is growing interest in the enzyme in...
10.
Le N, Foubert K, Theunis M, Naessens T, Bozdag M, Van der Veken P, et al.
ACS Omega
. 2024 Apr;
9(14):15971-15981.
PMID: 38617670
Walp. (Brassicaceae), also known as Maca or Peruvian ginseng, is a common ingredient in food supplements with many claimed health benefits, such as improved endurance, increased energy level, and enhanced...