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Patrick Conley

Explore the profile of Patrick Conley including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 219
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Recent Articles
1.
Newman R, Conley P, Esakoff T, Grobman W, Haas D, Wapner R, et al.
Am J Perinatol . 2025 Jan; PMID: 39884284
Objective:  The association between paternal age and adverse pregnancy outcomes (APOs) has not been well studied. We sought to determine whether advanced paternal age (APA) is associated with adverse maternal...
2.
Miller E, Conley P, Alirezaei M, Wolfova K, Gonzales M, Tan Z, et al.
Lancet Healthy Longev . 2024 Dec; 5(12):100660. PMID: 39675366
Background: Individuals with adverse pregnancy outcomes have an increased risk of cerebrovascular disease, but the association between adverse pregnancy outcomes and cognitive impairment and dementia is less well established. We...
3.
Ha L, Naqvi M, Conley P, Merz C, Gibbs B, Levine L, et al.
Am J Obstet Gynecol MFM . 2024 Aug; 6(10):101470. PMID: 39179158
Background: Activity restriction is a common recommendation given to patients during pregnancy for various indications, despite lack of definitive data showing improvements in pregnancy outcomes. Objective: To determine if activity...
4.
Anderson A, Conley P, Klocke C, Sengupta S, Pang A, Farley H, et al.
Biomark Res . 2024 Jul; 12(1):67. PMID: 39030653
Background: Uveal melanoma is the most common non-cutaneous melanoma and is an intraocular malignancy affecting nearly 7,000 individuals per year worldwide. Of these, approximately 50% will progress to metastatic disease...
5.
Orlic-Milacic M, Rothfels K, Matthews L, Wright A, Jassal B, Shamovsky V, et al.
Database (Oxford) . 2024 May; 2024. PMID: 38713862
Germline and somatic mutations can give rise to proteins with altered activity, including both gain and loss-of-function. The effects of these variants can be captured in disease-specific reactions and pathways...
6.
Anderson A, Conley P, Klocke C, Sengupta S, Pang A, Farley H, et al.
Res Sq . 2023 Dec; PMID: 38106024
Background: Uveal melanoma is the most common non-cutaneous melanoma and is an intraocular malignancy affecting nearly 7,000 individuals per year worldwide. Of these, approximately 50% will progress to metastatic disease...
7.
Anderson A, Conley P, Klocke C, Sengupta S, Robinson T, Fan Y, et al.
bioRxiv . 2023 Nov; PMID: 37961378
Uveal melanoma (UM) is the most common non-cutaneous melanoma and is an intraocular malignancy that affects nearly 7,000 individuals per year worldwide. Of these, nearly 50% will progress to metastatic...
8.
Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al.
Nucleic Acids Res . 2023 Nov; 52(D1):D672-D678. PMID: 37941124
The Reactome Knowledgebase (https://reactome.org), an Elixir and GCBR core biological data resource, provides manually curated molecular details of a broad range of normal and disease-related biological processes. Processes are annotated...
9.
Orlic-Milacic M, Rothfels K, Matthews L, Wright A, Jassal B, Shamovsky V, et al.
bioRxiv . 2023 Oct; PMID: 37904913
Disease variant annotation in the context of biological reactions and pathways can provide a standardized overview of molecular phenotypes of pathogenic mutations that is amenable to computational mining and mathematical...
10.
Beavers D, Brunson T, Sanati N, Matthews L, Haw R, Shorser S, et al.
Curr Protoc . 2023 Jul; 3(7):e845. PMID: 37467006
Understudied or dark proteins have the potential to shed light on as-yet undiscovered molecular mechanisms that underlie phenotypes and suggest innovative therapeutic approaches for many diseases. The Reactome-IDG (Illuminating the...