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Guanming Wu

Explore the profile of Guanming Wu including associated specialties, affiliations and a list of published articles. Areas
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Articles 73
Citations 11484
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Recent Articles
1.
Huffman A, Ong E, Brunson T, Sanati N, Zheng J, Masci A, et al.
CEUR Workshop Proc . 2024 Nov; 3603:1-12. PMID: 39583065
ImmPort, the world's largest repository of immunology data, includes many vaccine immune response datasets. ImmPort maps the metadata of these studies to ontology and database schema. As of February 28,...
2.
Anderson A, Conley P, Klocke C, Sengupta S, Pang A, Farley H, et al.
Biomark Res . 2024 Jul; 12(1):67. PMID: 39030653
Background: Uveal melanoma is the most common non-cutaneous melanoma and is an intraocular malignancy affecting nearly 7,000 individuals per year worldwide. Of these, approximately 50% will progress to metastatic disease...
3.
Evans N, Mills G, Wu G, Song X, McWeeney S
ArXiv . 2024 May; PMID: 38800649
High-quality data is crucial for accurate machine learning and actionable analytics, however, mislabeled or noisy data is a common problem in many domains. Distinguishing low- from high-quality data can be...
4.
Arora C, Matic M, Bisceglia L, Di Chiaro P, De Oliveira Rosa N, Carli F, et al.
Cell Genom . 2024 May; 4(5):100557. PMID: 38723607
We explored the dysregulation of G-protein-coupled receptor (GPCR) ligand systems in cancer transcriptomics datasets to uncover new therapeutics opportunities in oncology. We derived an interaction network of receptors with ligands...
5.
Orlic-Milacic M, Rothfels K, Matthews L, Wright A, Jassal B, Shamovsky V, et al.
Database (Oxford) . 2024 May; 2024. PMID: 38713862
Germline and somatic mutations can give rise to proteins with altered activity, including both gain and loss-of-function. The effects of these variants can be captured in disease-specific reactions and pathways...
6.
Evans N, Mills G, Wu G, Song X, McWeeney S
bioRxiv . 2024 Mar; PMID: 38464019
Availability And Implementation: Our implementation of the GSNN method is available at https://github.com/nathanieljevans/GSNN. All data used in this work is publicly available.
7.
Modak R, de Oliveira Rebola K, McClatchy J, Mohammadhosseini M, Damnernsawad A, Kurtz S, et al.
Clin Cancer Res . 2024 Mar; 30(10):2245-2259. PMID: 38451486
Purpose: Emerging evidence underscores the critical role of extrinsic factors within the microenvironment in protecting leukemia cells from therapeutic interventions, driving disease progression, and promoting drug resistance in acute myeloid...
8.
Niarakis A, Ostaszewski M, Mazein A, Kuperstein I, Kutmon M, Gillespie M, et al.
Front Immunol . 2024 Feb; 14:1282859. PMID: 38414974
Introduction: The COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop...
9.
Anderson A, Conley P, Klocke C, Sengupta S, Pang A, Farley H, et al.
Res Sq . 2023 Dec; PMID: 38106024
Background: Uveal melanoma is the most common non-cutaneous melanoma and is an intraocular malignancy affecting nearly 7,000 individuals per year worldwide. Of these, approximately 50% will progress to metastatic disease...
10.
Klocke C, Moran A, Adey A, McWeeney S, Wu G
bioRxiv . 2023 Nov; PMID: 38014233
While immune checkpoint inhibitors show success in treating a subset of patients with certain late-stage cancers, these treatments fail in many other patients as a result of mechanisms that have...