Pasi Virta
Overview
Explore the profile of Pasi Virta including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
72
Citations
320
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Afari M, Nurmi K, Virta P, Lonnberg T
ChemistryOpen
. 2023 Jul;
12(7):e202300085.
PMID: 37403132
Hairpin oligodeoxynucleotides incorporating a (2R,3S)-4-(methoxyamino)butane-1,2,3-triol residue in the middle of the double-helical stem and opposite to either one of the canonical nucleobases or an abasic 2-(hydroxymethyl)tetrahydrofuran-3-ol spacer were synthesized. Under...
12.
Aho A, Virta P
Chem Commun (Camb)
. 2023 Apr;
59(38):5689-5692.
PMID: 37078964
Reversible pH-responsive -methoxyoxazolidine formation is used to ligate split aptamer fragments. Two twice-split models and one thrice-split model of CBA (cocaine-binding aptamer) were examined. The aptamer assembly was dynamic, proportional...
13.
Artukka E, Schnell R, Palmu K, Rosenqvist P, Szodorai E, Niemi J, et al.
ACS Chem Biol
. 2023 Apr;
18(4):794-802.
PMID: 37005433
Pseudouridimycin is a microbial -nucleoside natural product that specifically inhibits bacterial RNA polymerases by binding to the active site and competing with uridine triphosphate for the nucleoside triphosphate (NTP) addition...
14.
Rosenqvist P, Makinen J, Palmu K, Jokinen J, Prajapati R, Korhonen H, et al.
Eur J Med Chem
. 2022 Apr;
237:114342.
PMID: 35439612
Showdomycin produced by Streptomyces showdoensis ATCC 15227 is a C-nucleoside microbial natural product with antimicrobial and cytotoxic properties. The unique feature of showdomycin in comparison to other nucleosides is its...
15.
Suchsland R, Appel B, Virta P, Muller S
RSC Adv
. 2022 Apr;
11(7):3892-3896.
PMID: 35424330
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained...
16.
Afari M, Virta P, Lonnberg T
Org Biomol Chem
. 2022 Apr;
20(17):3480-3485.
PMID: 35388869
(2,3)-4-(Methoxyamino)butane-1,2,3-triol was converted into a protected phosphoramidite building block and incorporated into the middle of a short DNA oligonucleotide. O1 and O3 of the (2,3)-4-(methoxyamino)butane-1,2,3-triol were engaged in phosphodiester linkages,...
17.
Gomez-Raya-Vilanova M, Leskinen K, Bhattacharjee A, Virta P, Rosenqvist P, Smith J, et al.
Nucleic Acids Res
. 2022 Mar;
50(7):3985-3997.
PMID: 35357498
Yersinia phage YerA41 is morphologically similar to jumbo bacteriophages. The isolated genomic material of YerA41 could not be digested by restriction enzymes, and used as a template by conventional DNA...
18.
Gulumkar V, Tahtinen V, Ali A, Rahkila J, Valle-Delgado J, Aarela A, et al.
ACS Omega
. 2022 Jan;
7(1):1329-1336.
PMID: 35036794
Bingel cyclopropanation between Buckminster fullerene and a heteroarmed malonate was utilized to produce a hexakis-functionalized C core, with azide and tetrazine units. This orthogonally bifunctional C scaffold can be selectively...
19.
Tahtinen V, Gulumkar V, Maity S, Yliperttula A, Siekkinen S, Laine T, et al.
Bioconjug Chem
. 2022 Jan;
33(1):206-218.
PMID: 34985282
Glyco-decorated spherical nucleic acids (SNAs) may be attractive delivery vehicles, emphasizing the sugar-specific effect on the outer sphere of the construct and at the same time hiding unfavorable distribution properties...
20.
Aro-Heinila A, Lepisto A, Aarela A, Lonnberg T, Virta P
J Org Chem
. 2021 Dec;
87(1):137-146.
PMID: 34905374
A 2-trifluoromethylaniline C-nucleoside was synthesized, incorporated in the middle of an oligonucleotide, and mercurated. The affinity of the mercurated oligonucleotide toward complementary strands placing each of the canonical nucleobases opposite...