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Anne Roivainen

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Articles 161
Citations 2353
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Recent Articles
1.
Auchynnikava T, Aarela A, Moisio O, Liljenback H, Andriana P, Iqbal I, et al.
ACS Omega . 2025 Feb; 10(6):6003-6014. PMID: 39989783
Folate receptors (FRs), membrane-bound proteins that bind specifically to folate with high affinity, are overexpressed by various cancer types and are therefore used as targets for delivery of therapeutic agents....
2.
Uurasmaa T, Bourdin P, Nammas W, Latifi S, Liljenback H, Saraste A, et al.
J Transl Med . 2025 Jan; 23(1):89. PMID: 39838445
Introduction: Doxorubicin is a chemotherapeutic drug used to treat various cancers. Exercise training (ET) can attenuate some cardiotoxic effects of doxorubicin (DOX) in tumor-free animals. However, the ET effects on...
3.
Dadson P, Honka M, Suomi T, Haridas P, Rokka A, Palani S, et al.
Am J Physiol Endocrinol Metab . 2025 Jan; 328(3):E311-E324. PMID: 39819027
In this study, we investigated the impact of bariatric surgery on the adipose proteome to better understand the metabolic and cellular mechanisms underlying weight loss following the procedure. A total...
4.
Dillemuth P, Lovdahl P, Karskela T, Ayo A, Ponkamo J, Liljenback H, et al.
Mol Pharm . 2024 Jul; 21(8):4147-4156. PMID: 39008899
Fatty acid binding protein 3 (FABP3) is expressed both in tumor cells and in the tumor vasculature, making it a potential target for medical imaging and therapy. In this study,...
5.
Bellman J, Sjoros T, Hagg D, Atencio Herre E, Hieta J, Eskola O, et al.
J Clin Endocrinol Metab . 2024 May; 109(12):3126-3136. PMID: 38753869
Context: Increased standing time has been associated with improved health, but the underlying mechanism is unclear. Objectives: We herein investigate if increased weight loading increases energy demand and thereby glucose...
6.
Hess S, Noriega-Alvarez E, Leccisotti L, Treglia G, Albano D, Roivainen A, et al.
Eur J Nucl Med Mol Imaging . 2024 Apr; 51(9):2597-2613. PMID: 38676736
Purpose: Patients with fever and inflammation of unknown origin (FUO/IUO) are clinically challenging due to variable clinical presentations with nonspecific symptoms and many differential diagnoses. Positron emission tomography/computed tomography (PET/CT)...
7.
Saraste A, Stahle M, Roivainen A, Knuuti J
Semin Nucl Med . 2024 Apr; 54(5):674-685. PMID: 38609753
Molecular imaging can detect and quantify pathophysiological processes underlying heart failure, complementing evaluation of cardiac structure and function with other imaging modalities. Targeted tracers have enabled assessment of various cellular...
8.
Andriana P, Fair-Makela R, Liljenback H, Karna S, Iqbal I, Makrypidi K, et al.
Eur J Nucl Med Mol Imaging . 2024 Mar; 51(8):2216-2228. PMID: 38532026
Purpose: Aluminum fluoride-18-labeled 1,4,7-triazacyclononane-1,4,7-triacetic acid-conjugated mannosylated dextran derivative (Al[F]F-NOTA-D10CM) is a new tracer for PET imaging. We report here on in vitro and in vivo validation of the tracer's ability...
9.
Dillemuth P, Karskela T, Ayo A, Ponkamo J, Kunnas J, Rajander J, et al.
EJNMMI Radiopharm Chem . 2024 Feb; 9(1):16. PMID: 38393497
Background: Fatty acid binding protein 3 (FABP3) is a target with clinical relevance and the peptide ligand ACooP has been identified for FABP3 targeting. ACooP is a linear decapeptide containing...
10.
Bhowmik A, Heikkila T, Polari L, Virta J, Liljenback H, Moisio O, et al.
Mol Imaging Biol . 2023 Dec; 26(2):322-333. PMID: 38110791
Purpose: Inflammatory bowel disease (IBD) can be imaged with positron emission tomography (PET), but existing PET radiopharmaceuticals have limited diagnostic accuracy. Vascular adhesion protein-1 (VAP-1) is an endothelial cell surface...