Acs Chemical Biology
Overview
ACS Chemical Biology is a peer-reviewed scientific journal that publishes cutting-edge research at the interface of chemistry and biology. It covers a wide range of topics, including chemical biology, bioorganic chemistry, synthetic biology, and drug discovery. The journal aims to advance our understanding of biological systems and develop innovative approaches to address complex biological problems.
Details
Details
Abbr.
ACS Chem Biol
Publisher
American Chemical Society
Start
2006
End
Continuing
Frequency
Monthly
p-ISSN
1554-8929
e-ISSN
1554-8937
Country
United States
Language
English
Specialties
Biochemistry
Biology
Biology
Metrics
Metrics
h-index / Ranks: 1773
135
SJR / Ranks: 2330
1344
CiteScore / Ranks: 2478
7.60
JIF / Ranks: 2264
4.0
Recent Articles
1.
Tong H, Ma Z, Yu J, Li D, Zhu Q, Shi H, et al.
ACS Chem Biol
. 2025 Mar;
PMID: 40080657
Glioblastoma multiforme (GBM) is a WHO grade 4 glioma and the most common malignant primary brain tumor. Addressing the clinical management of GBM presents an exceptionally daunting and intricate challenge,...
2.
Sun X, Kleiner R
ACS Chem Biol
. 2025 Mar;
PMID: 40079837
Post-transcriptional modifications on RNA play an important role in biological processes, but we lack an understanding of the molecular mechanisms underlying the function of many modifications. Here we characterize the...
3.
Nie P, Wu Y, Robinson J, Mekala S, Lee V, Li Y
ACS Chem Biol
. 2025 Mar;
PMID: 40079621
Tau aggregation plays a crucial role in the development of Alzheimer's disease (AD). Developing specific techniques that can isolate pathogenic tau from brain tissue is important for understanding tauopathies and...
4.
Lemmex A, Allred J, Ostergard J, Trask J, Bui H, Anderson M, et al.
ACS Chem Biol
. 2025 Mar;
PMID: 40079390
Notch plays critical roles in developmental processes and disease pathogenesis, which have led to numerous efforts to modulate its function with small molecules and antibodies. Here we present a nanobody...
5.
Emanuelson C, Naro Y, Shade O, Liu M, Khare S, Deiters A
ACS Chem Biol
. 2025 Mar;
PMID: 40063062
Human Papillomavirus (HPV) is linked to multiple cancers, most significantly cervical cancer, for which HPV infection is associated with nearly all cases. Essential to the oncogenesis of HPV is the...
6.
Micheloni E, Watson S, Beuning P, Ondrechen M
ACS Chem Biol
. 2025 Mar;
PMID: 40059726
Human ornithine transcarbamylase deficiency (OTCD) is the most common ureagenesis disorder in the world. OTCD is an X-linked genetic deficiency in which patients experience hyperammonemia to varying degrees depending on...
7.
Ovechkina V, Andrianova S, Shimanskaia I, Suvorova P, Ryabinina A, Blagonravov M, et al.
ACS Chem Biol
. 2025 Mar;
PMID: 40056098
Optogenetics and chemogenetics are relatively new biomedical technologies that emerged 20 years ago and have been evolving rapidly since then. This has been made possible by the combined use of...
8.
Tjallinks G, Angeleri N, Nguyen Q, Mannucci B, Arentshorst M, Visser J, et al.
ACS Chem Biol
. 2025 Mar;
PMID: 40052414
Sorbicillinoids are yellow secondary metabolites synthesized through an elegant combination of enzymatic and spontaneous biochemical processes. The flavin-dependent monooxygenase SorC and oxidase SorD are crucial in this interplay, enabling the...
9.
Awale S, Maneenet J, Phan N, Nguyen H, Fujii T, Ihmels H, et al.
ACS Chem Biol
. 2025 Mar;
PMID: 40048237
Pancreatic cancer is a highly aggressive and lethal malignancy, with a 5-year survival rate below 10%. Traditional chemotherapy, including gemcitabine, has limited efficacy due to chemoresistance and a unique tumor...
10.
Ding Y, Perez-Ortiz G, Butulan A, Sharif H, Barry S
ACS Chem Biol
. 2025 Mar;
PMID: 40048149
The nonribosomal cyclic peptides (NRcPs) rufomycins, produced by , have attracted attention as antimycobacterials. Thus, there has been interest in engineering the corresponding biosynthetic pathway to produce novel derivatives. We...