Tuomas Lonnberg
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Explore the profile of Tuomas Lonnberg including associated specialties, affiliations and a list of published articles.
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58
Citations
196
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Recent Articles
1.
Uttam Ukale D, Lonnberg T
Chembiochem
. 2025 Feb;
:e202401006.
PMID: 39910831
Homothymidine DNA oligonucleotides bearing a 3'-terminal 6-phenyl-9H-carbazole C-nucleoside, mercurated at position 1, 8 or both, were synthesized and tested for their potential to form triple helices with homoadenine ⋅ homothymine...
2.
Kahkola H, Herath M, Virta P, Lonnberg T
Org Biomol Chem
. 2025 Jan;
23(7):1714-1722.
PMID: 39804526
In this article, a neoacetalization-based method for post-SELEX modification of aptamers is introduced. Three modified quinine binding aptamer scaffolds were synthesized by replacing three different nucleosides of the binding site...
3.
Kotammagari T, Al-Waeel M, Lukkari J, Lonnberg T
RSC Adv
. 2024 Dec;
14(51):38279-38284.
PMID: 39628462
A fluorescently tagged oligonucleotide hybridization probe incorporating a single 5-mercuricytosine residue was synthesized and found to adsorb on polydopamine nanoparticles much more strongly than its unmetallated counterpart. Hybridization with target...
4.
Afari M, Heikinmaki N, Virta P, Lonnberg T
Chembiochem
. 2024 Sep;
26(1):e202400666.
PMID: 39243158
Various single-stranded and hairpin-forming DNA and 2'-O-methyl-RNA oligonucleotides bearing a single (2R,3S)-4-(methoxyamino)butane-1,2,3-triol residue esterified from either O1 and O2 or O1 and O3 were synthesized. Incubation of these oligonucleotides with...
5.
Afari M, Lonnberg T
ChemistryOpen
. 2024 May;
13(9):e202400088.
PMID: 38709096
Base-filling, i. e., post-synthetic furnishing of an oligonucleotide scaffold with base moieties or their analogues, is an interesting alternative to the conventional approach of sequential coupling of building blocks (modified...
6.
Kotammagari T, Saleh L, Lonnberg T
Chem Commun (Camb)
. 2024 Feb;
60(23):3118-3128.
PMID: 38385213
To improve their properties or to introduce entirely new functionalities, the intriguing scaffolds of nucleic acids have been decorated with various modifications, most recently also organometallic ones. While challenging to...
7.
Saleh L, Ora M, Lonnberg T
J Inorg Biochem
. 2023 Jul;
247:112331.
PMID: 37480764
Two oligonucleotide conjugates sharing the same sequence but incorporating a different 5'-terminal organometallic moiety were synthesized, by either direct mercuration in solution or oximation with an organomercury aldehyde on solid...
8.
Afari M, Nurmi K, Virta P, Lonnberg T
ChemistryOpen
. 2023 Jul;
12(7):e202300085.
PMID: 37403132
Hairpin oligodeoxynucleotides incorporating a (2R,3S)-4-(methoxyamino)butane-1,2,3-triol residue in the middle of the double-helical stem and opposite to either one of the canonical nucleobases or an abasic 2-(hydroxymethyl)tetrahydrofuran-3-ol spacer were synthesized. Under...
9.
Kotammagari T, Tahtinen P, Lonnberg T
Chemistry
. 2022 Sep;
28(69):e202202530.
PMID: 36108095
Short oligonucleotides incorporating either 1-mercuri-6-phenylcarbazole, 8-mercuri-6-phenylcarbazole, or 1,8-dimercuri-6-phenylcarbazole C-nucleoside in the middle of the chain have been synthesized and studied for their potential as hybridization probes for sequences containing thiopyrimidine...
10.
Afari M, Virta P, Lonnberg T
Org Biomol Chem
. 2022 Apr;
20(17):3480-3485.
PMID: 35388869
(2,3)-4-(Methoxyamino)butane-1,2,3-triol was converted into a protected phosphoramidite building block and incorporated into the middle of a short DNA oligonucleotide. O1 and O3 of the (2,3)-4-(methoxyamino)butane-1,2,3-triol were engaged in phosphodiester linkages,...