P Scott Hefty
Overview
Explore the profile of P Scott Hefty including associated specialties, affiliations and a list of published articles.
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41
Citations
955
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Recent Articles
1.
Hall K, Kenedy M, Johnson D, Hefty P, Akins D
PLoS One
. 2024 Aug;
19(8):e0304839.
PMID: 39208212
Lyme disease is the leading tick-borne infection in the United States, caused by the pathogenic spirochete Borreliella burgdorferi, formerly known as Borrelia burgdorferi. Diderms, or bacteria with dual-membrane ultrastructure, such...
2.
Weeramange C, Menjivar C, ONeil P, El Qaidi S, Harrison K, Meinhardt S, et al.
J Biol Chem
. 2024 May;
300(6):107352.
PMID: 38723750
In Escherichia coli, the master transcription regulator catabolite repressor activator (Cra) regulates >100 genes in central metabolism. Cra binding to DNA is allosterically regulated by binding to fructose-1-phosphate (F-1-P), but...
3.
Weeramange C, Menjivar C, ONeil P, El Qaidi S, Harrison K, Meinhardt S, et al.
bioRxiv
. 2024 Jan;
PMID: 38168282
In , the master transcription regulator Catabolite Repressor Activator (Cra) regulates >100 genes in central metabolism. Cra binding to DNA is allosterically regulated by binding to fructose-1-phosphate (F-1-P), but the...
4.
Baid S, Hefty P, Morgan D
J Microbiol Biol Educ
. 2022 Sep;
23(2).
PMID: 36061320
During the COVID-19 pandemic, universities across the globe quickly shifted to online education. Laboratory courses faced unique challenges and were forced to reevaluate learning objectives and identify creative projects to...
5.
Dimond Z, Suchland R, Baid S, LaBrie S, Soules K, Stanley J, et al.
Mol Microbiol
. 2021 Nov;
116(6):1433-1448.
PMID: 34738268
Chlamydia muridarum actively grows in murine mucosae and is a representative model of human chlamydial genital tract disease. In contrast, C. trachomatis infections in mice are limited and rarely cause...
6.
Smaili F, Tian S, Roy A, Alazmi M, Arold S, Mukherjee S, et al.
Genomics Proteomics Bioinformatics
. 2021 Feb;
19(6):998-1011.
PMID: 33631427
The number of available protein sequences in public databases is increasing exponentially. However, a significant percentage of these sequences lack functional annotation, which is essential for the understanding of how...
7.
Soules K, LaBrie S, May B, Hefty P
mBio
. 2020 Sep;
11(5).
PMID: 32900805
bacteria are obligate intracellular organisms with a phylum-defining biphasic developmental cycle that is intrinsically linked to its ability to cause disease. The progression of the chlamydial developmental cycle is regulated...
8.
Dimond Z, Hefty P
Pathog Dis
. 2020 Jul;
79(2).
PMID: 32639528
Chlamydia suis, a ubiquitous swine pathogen, has the potential for zoonotic transmission to humans and often encodes for resistance to the primary treatment antibiotic, tetracycline. Because of this emerging threat,...
9.
Soules K, Dmitriev A, LaBrie S, Dimond Z, May B, Johnson D, et al.
Mol Microbiol
. 2019 Oct;
113(1):68-88.
PMID: 31637787
Chlamydia trachomatis is an obligate intracellular bacteria that undergo dynamic morphologic and physiologic conversions upon gaining an access to a eukaryotic cell. These conversions likely require the detection of key...
10.
Suchland R, Carrell S, Wang Y, Hybiske K, Kim D, Dimond Z, et al.
J Bacteriol
. 2019 Sep;
201(23).
PMID: 31501285
Lateral gene transfer (LGT) among strains is common, in both isolates generated in the laboratory and those examined directly from patients. In contrast, there are very few examples of recent...