Robert J Suchland
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Explore the profile of Robert J Suchland including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Fernandez M, Sweeney Y, Suchland R, Carrell S, Soge O, Phan I, et al.
iScience
. 2024 Jul;
27(6):110143.
PMID: 38947519
Evading host innate immune defenses is a critical feature of infections, and the mechanisms used by to subvert these pathways are incompletely understood. We screened a library of chimeric mutants...
2.
DeBoer A, Lei L, Yang C, Martens C, Anzick S, Antonioli-Schmit S, et al.
Infect Immun
. 2023 May;
91(7):e0009623.
PMID: 37255490
All members of the family Chlamydiaceae have lipopolysaccharides (LPS) that possess a shared carbohydrate trisaccharide antigen, 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) that is functionally uncharacterized. A single gene, genus-specific epitope (), is...
3.
Suchland R, Carrell S, Ramsey S, Hybiske K, Debrine A, Sanchez J, et al.
Infect Immun
. 2022 Oct;
90(11):e0026522.
PMID: 36214558
Chlamydia trachomatis is an obligate intracellular bacterium that causes serious diseases in humans. Rectal infection and disease caused by this pathogen are important yet understudied aspects of C. trachomatis natural...
4.
Marti H, Suchland R, Rockey D
Front Cell Infect Microbiol
. 2022 Mar;
12:861899.
PMID: 35321311
Lateral gene transfer (LGT) facilitates many processes in bacterial ecology and pathogenesis, especially regarding pathogen evolution and the spread of antibiotic resistance across species. The obligate intracellular chlamydiae, which cause...
5.
Dimond Z, Suchland R, Baid S, LaBrie S, Soules K, Stanley J, et al.
Mol Microbiol
. 2021 Nov;
116(6):1433-1448.
PMID: 34738268
Chlamydia muridarum actively grows in murine mucosae and is a representative model of human chlamydial genital tract disease. In contrast, C. trachomatis infections in mice are limited and rarely cause...
6.
McQueen B, Kiatthanapaiboon A, Fulcher M, Lam M, Patton K, Powell E, et al.
Infect Immun
. 2020 Jul;
88(9).
PMID: 32601108
infection of the human fallopian tubes can lead to damaging inflammation and scarring, ultimately resulting in infertility. To study the human cellular responses to chlamydial infection, researchers have frequently used...
7.
8.
Suchland R, Carrell S, Wang Y, Hybiske K, Kim D, Dimond Z, et al.
J Bacteriol
. 2019 Sep;
201(23).
PMID: 31501285
Lateral gene transfer (LGT) among strains is common, in both isolates generated in the laboratory and those examined directly from patients. In contrast, there are very few examples of recent...
9.
Wang Y, LaBrie S, Carrell S, Suchland R, Dimond Z, Kwong F, et al.
J Bacteriol
. 2019 Sep;
201(23).
PMID: 31501283
Functional genetic analysis of has been a challenge due to the historical genetic intractability of , although recent advances in chlamydial genetic manipulation have begun to remove these barriers. Here,...
10.
LaBrie S, Dimond Z, Harrison K, Baid S, Wickstrum J, Suchland R, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31387908
Transposon mutagenesis is a widely applied and powerful genetic tool for the discovery of genes associated with selected phenotypes. is a clinically significant, obligate intracellular bacterium for which many conventional...