Olivier B Poirion
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Explore the profile of Olivier B Poirion including associated specialties, affiliations and a list of published articles.
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18
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1314
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Recent Articles
1.
Delorme A, Poirion O, Lebreton L, le Gac P, Kane K, Royer S
Mar Pollut Bull
. 2025 Feb;
214:117712.
PMID: 40020394
Global models estimate that two-thirds of floating ocean plastic has accumulated in coastal areas since the 1950s, with Hawai'i's windward shores particularly vulnerable due to their proximity to the North...
2.
Kim H, Rosenthal S, Liu X, Miciano C, Hou X, Miller M, et al.
J Hepatol
. 2024 Nov;
PMID: 39522884
Background & Aims: Metabolic dysfunction-associated steatotic liver disease ranges from metabolic dysfunction-associated steatotic liver (MASL) to metabolic dysfunction-associated steatohepatitis (MASH) with fibrosis. Transdifferentiation of hepatic stellate cells (HSCs) into fibrogenic...
3.
Poirion O, Zuo W, Spruce C, Baker C, Daigle S, Olson A, et al.
Genome Biol
. 2024 Sep;
25(1):235.
PMID: 39223609
Enhlink is a computational tool for scATAC-seq data analysis, facilitating precise interrogation of enhancer function at the single-cell level. It employs an ensemble approach incorporating technical and biological covariates to...
4.
Destici E, Zhu F, Tran S, Preissl S, Farah E, Zhang Y, et al.
Nat Cardiovasc Res
. 2024 Aug;
1(12):1231.
PMID: 39196171
No abstract available.
5.
Xie F, Armand E, Yao Z, Liu H, Bartlett A, Margarita Behrens M, et al.
Cell Genom
. 2023 Jul;
3(7):100342.
PMID: 37492103
Single-cell sequencing could help to solve the fundamental challenge of linking millions of cell-type-specific enhancers with their target genes. However, this task is confounded by patterns of gene co-expression in...
6.
Poirion O, Zuo W, Spruce C, Daigle S, Olson A, Skelly D, et al.
bioRxiv
. 2023 May;
PMID: 37214950
Enhancers play a crucial role in regulating gene expression and their functional status can be queried with cell type precision using using single-cell (sc)ATAC-seq. To facilitate analysis of such data,...
7.
Destici E, Zhu F, Tran S, Preissl S, Farah E, Zhang Y, et al.
Nat Cardiovasc Res
. 2023 Feb;
1(9):830-843.
PMID: 36817700
The heart, a vital organ which is first to develop, has adapted its size, structure and function in order to accommodate the circulatory demands for a broad range of animals....
8.
Zhang K, Hocker J, Miller M, Hou X, Chiou J, Poirion O, et al.
Cell
. 2021 Nov;
184(24):5985-6001.e19.
PMID: 34774128
Current catalogs of regulatory sequences in the human genome are still incomplete and lack cell type resolution. To profile the activity of gene regulatory elements in diverse cell types and...
9.
Li Y, Preissl S, Hou X, Zhang Z, Zhang K, Qiu Y, et al.
Nature
. 2021 Oct;
598(7879):129-136.
PMID: 34616068
The mammalian cerebrum performs high-level sensory perception, motor control and cognitive functions through highly specialized cortical and subcortical structures. Recent surveys of mouse and human brains with single-cell transcriptomics and...
10.
Liu H, Zhou J, Tian W, Luo C, Bartlett A, Aldridge A, et al.
Nature
. 2021 Oct;
598(7879):120-128.
PMID: 34616061
Mammalian brain cells show remarkable diversity in gene expression, anatomy and function, yet the regulatory DNA landscape underlying this extensive heterogeneity is poorly understood. Here we carry out a comprehensive...