Kyle J Gaulton
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Explore the profile of Kyle J Gaulton including associated specialties, affiliations and a list of published articles.
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85
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6179
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Recent Articles
1.
Melton R, Jimenez S, Elison W, Tucciarone L, Howell A, Wang G, et al.
bioRxiv
. 2025 Mar;
PMID: 40027657
Cell type-specific regulatory programs that drive type 1 diabetes (T1D) in the pancreas are poorly understood. Here we performed single nucleus multiomics and spatial transcriptomics in up to 32 non-diabetic...
2.
McGrail C, Chiou J, Egamal R, Elgamal R, Luckett A, Oram R, et al.
Diabetes Care
. 2024 Dec;
48(2):202-211.
PMID: 39626097
Objective: More than 10% of patients with type 1 diabetes (T1D) do not have high-risk HLA-DR3 or -DR4 haplotypes with distinct clinical features, such as later onset and reduced insulin...
3.
Qadir M, Elgamal R, Song K, Kudtarkar P, Sakamuri S, Katakam P, et al.
EMBO J
. 2024 Nov;
43(24):6364-6382.
PMID: 39567827
Patients with type 2 and type 1 diabetes (T2D and T1D) exhibit sex-specific differences in insulin secretion, the mechanisms of which are unknown. We examined sex differences in human pancreatic...
4.
Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin J, et al.
Cell Stem Cell
. 2024 Aug;
31(10):1465-1483.e6.
PMID: 39181129
While all eukaryotic cells are dependent on mitochondria for function, in a complex tissue, which cell type and which cell behavior are more sensitive to mitochondrial deficiency remain unpredictable. Here,...
5.
Mummey H, Elison W, Korgaonkar K, Elgamal R, Kudtarkar P, Griffin E, et al.
bioRxiv
. 2024 Aug;
PMID: 39149326
Physiological variability in pancreatic cell type gene regulation and the impact on diabetes risk is poorly understood. In this study we mapped gene regulation in pancreatic cell types using single...
6.
Elgamal R, Melton R, Chiou J, McGrail C, Gaulton K
medRxiv
. 2024 Aug;
PMID: 39148858
Novel biomarkers of type 1 diabetes (T1D) are needed for earlier detection of disease and identifying therapeutic targets. We identified biomarkers of T1D by combining plasma and protein QTLs (pQTLs)...
7.
Qadir M, Elgamal R, Song K, Kudtarkar P, Sakamuri S, Katakam P, et al.
Res Sq
. 2024 Jul;
PMID: 39011095
Type 2 and type 1 diabetes (T2D, T1D) exhibit sex differences in insulin secretion, the mechanisms of which are unknown. We examined sex differences in human pancreatic islets from 52...
8.
Robertson C, Elgamal R, Henry-Kanarek B, Arvan P, Chen S, Dhawan S, et al.
Mol Metab
. 2024 Jun;
86:101973.
PMID: 38914291
Background: Type 1 diabetes (T1D) is a complex multi-system disease which arises from both environmental and genetic factors, resulting in the destruction of insulin-producing pancreatic beta cells. Over the past...
9.
Ament S, Campbell R, Lobo M, Receveur J, Agrawal K, Borjabad A, et al.
Mol Psychiatry
. 2024 Jun;
29(12):3950-3961.
PMID: 38879719
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One...
10.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, et al.
Nat Med
. 2024 May;
30(7):2091.
PMID: 38760590
No abstract available.