Nicholas A Cilfone
Overview
Explore the profile of Nicholas A Cilfone including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
851
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pradines J, Farutin V, Cilfone N, Ghavami A, Kurtagic E, Guess J, et al.
PLoS Comput Biol
. 2020 Feb;
16(2):e1007684.
PMID: 32058996
Identification of differentially expressed genes (DEGs) is well recognized to be variable across independent replications of genome-wide transcriptional studies. These are often employed to characterize disease state early in the...
2.
Li G, Wang M, Caulk A, Cilfone N, Gujja S, Qin L, et al.
J Clin Invest
. 2020 Feb;
130(3):1233-1251.
PMID: 32039915
Smooth muscle cell (SMC) proliferation has been thought to limit the progression of thoracic aortic aneurysm and dissection (TAAD) because loss of medial cells associates with advanced disease. We investigated...
3.
Farutin V, Prodhomme T, McConnell K, Washburn N, Halvey P, Etzel C, et al.
Arthritis Res Ther
. 2019 Oct;
21(1):216.
PMID: 31647025
Background: The goal of this study is to use comprehensive molecular profiling to characterize clinical response to anti-TNF therapy in a real-world setting and identify reproducible markers differentiating good responders...
4.
Chen P, Qin L, Li G, Wang Z, Dahlman J, Malagon-Lopez J, et al.
Nat Metab
. 2019 Oct;
1(9):912-926.
PMID: 31572976
Atherosclerosis is a progressive vascular disease triggered by interplay between abnormal shear stress and endothelial lipid retention. A combination of these and, potentially, other factors leads to a chronic inflammatory...
5.
Ricard N, Scott R, Booth C, Velazquez H, Cilfone N, Baylon J, et al.
J Exp Med
. 2019 Jun;
216(8):1874-1890.
PMID: 31196980
To define the role of ERK1/2 signaling in the quiescent endothelium, we induced endothelial knockout in adult mice. This resulted in a rapid onset of hypertension, a decrease in eNOS...
6.
Baylon J, Cilfone N, Gulcher J, Chittenden T
J Chem Inf Model
. 2019 Jan;
59(2):673-688.
PMID: 30642173
Chemical synthesis planning is a key aspect in many fields of chemistry, especially drug discovery. Recent implementations of machine learning and artificial intelligence techniques for retrosynthetic analysis have shown great...
7.
Ling L, Hillson J, Tiessen R, Bosje T, van Iersel M, Nix D, et al.
Clin Pharmacol Ther
. 2018 Nov;
105(4):1031-1039.
PMID: 30402880
M281 is a fully human, anti-neonatal Fc receptor (FcRn) antibody that inhibits FcRn-mediated immunoglobulin G (IgG) recycling to decrease pathogenic IgG while preserving IgG production. A randomized, double-blind, placebo-controlled, first-in-human...
8.
Cicchese J, Evans S, Hult C, Joslyn L, Wessler T, Millar J, et al.
Immunol Rev
. 2018 Aug;
285(1):147-167.
PMID: 30129209
Immune responses to pathogens are complex and not well understood in many diseases, and this is especially true for infections by persistent pathogens. One mechanism that allows for long-term control...
9.
Ip B, Cilfone N, Belkina A, Defuria J, Jagannathan-Bogdan M, Zhu M, et al.
Obesity (Silver Spring)
. 2015 Nov;
24(1):102-12.
PMID: 26576827
Objective: T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM). The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding...
10.
Cilfone N, Kirschner D, Linderman J
Cell Mol Bioeng
. 2015 Sep;
8(1):119-136.
PMID: 26366228
Biologically related processes operate across multiple spatiotemporal scales. For computational modeling methodologies to mimic this biological complexity, individual scale models must be linked in ways that allow for dynamic exchange...