George Tellides
Overview
Explore the profile of George Tellides including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
5439
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Recent Articles
1.
Ramachandra A, Sharma P, De Man R, Nikola F, Guerrera N, Doddaballapur P, et al.
bioRxiv
. 2025 Mar;
PMID: 40027757
Hypoxemia impairs cardiopulmonary function. We investigated pulmonary artery remodeling in mice exposed to chronic hypoxia for up to five weeks and quantified associated changes in cardiac and lung function, without...
2.
Jiang B, Ren P, He C, Wang M, Murtada S, Ruiz-Rodriguez M, et al.
JCI Insight
. 2025 Feb;
PMID: 39932797
Hypertension and transient increases in blood pressure from extreme exertion are risk factors for aortic dissection in patients with age-related vascular degeneration or inherited connective tissue disorders. Yet, a common...
3.
Ren P, Jiang B, Hassab A, Hassab A, Li G, Li W, et al.
Arterioscler Thromb Vasc Biol
. 2024 Dec;
45(2):260-276.
PMID: 39697172
Background: Smooth muscle cells (SMCs) of cardiac and neural crest origin contribute to the developing proximal aorta and are linked to disease propensity in adults. Methods: We analyzed single-cell transcriptomes...
4.
Batty L, Park J, Qin L, Riaz M, Lin Y, Xu Z, et al.
Acta Biomater
. 2024 Dec;
193:171-184.
PMID: 39681154
Induced pluripotent stem cells (iPSCs) hold great promise for the treatment of cardiovascular diseases through cell-based therapies, but these therapies require extensive preclinical testing that is best done in species-in-species...
5.
Park J, Riaz M, Qin L, Zhang W, Batty L, Fooladi S, et al.
Cell Stem Cell
. 2024 Dec;
32(1):137-143.e6.
PMID: 39644899
Tissue-engineered vascular conduits (TEVCs), often made by seeding autologous bone marrow cells onto biodegradable polymeric scaffolds, hold promise toward treating single-ventricle congenital heart defects (SVCHDs). However, the clinical adoption of...
6.
Zhang W, Gonzalez L, Li X, Bai H, Li Z, Taniguchi R, et al.
Arterioscler Thromb Vasc Biol
. 2024 Sep;
44(12):2509-2526.
PMID: 39297205
Background: Arteriovenous fistulae (AVF) are the preferred vascular access for hemodialysis in patients with end-stage kidney disease. Chronic kidney disease (CKD) is associated with endothelial injury, impaired AVF maturation, and...
7.
Lee S, Schleer H, Park H, Jang E, Boyer M, Tao B, et al.
Nat Cardiovasc Res
. 2024 Aug;
2(5):438-448.
PMID: 39196046
Low-density lipoprotein (LDL) accumulation in the arterial wall contributes to atherosclerosis initiation and progression. Activin A receptor-like type 1 (ACVRL1, called activin-like kinase receptor (ALK1)) is a recently identified receptor...
8.
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, et al.
Physiol Rep
. 2024 Jun;
12(12):e16090.
PMID: 38884325
Adverse effects of large artery stiffening are well established in the systemic circulation; stiffening of the proximal pulmonary artery (PPA) and its sequelae are poorly understood. We combined in vivo...
9.
Multiscale computational model of aortic remodeling following postnatal disruption of TGFβ signaling
Estrada A, Irons L, Tellides G, Humphrey J
J Biomech
. 2024 May;
169:112152.
PMID: 38763809
The healthy adult aorta is a remarkably resilient structure, able to resist relentless cardiac-induced and hemodynamic loads under normal conditions. Fundamental to such mechanical homeostasis is the mechano-sensitive cell signaling...
10.
Ellis M, Riaz M, Huang Y, Anderson C, Hoareau M, Li X, et al.
Arterioscler Thromb Vasc Biol
. 2024 May;
44(7):1674-1682.
PMID: 38752350
Background: A series of incurable cardiovascular disorders arise due to improper formation of elastin during development. Supravalvular aortic stenosis (SVAS), resulting from a haploinsufficiency of , is caused by improper...