Denise E Kirschner
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Explore the profile of Denise E Kirschner including associated specialties, affiliations and a list of published articles.
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95
Citations
3453
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Recent Articles
1.
Michael C, Almohri S, Linderman J, Kirschner D
Front Syst Biol
. 2024 Sep;
3.
PMID: 39310676
HostSim: . HostSim HostSim
2.
Nanda P, Kirschner D
Front Appl Math Stat
. 2024 Jan;
9.
PMID: 38222943
Mathematical and computational models of biological systems are increasingly complex, typically comprised of hybrid multi-scale methods such as ordinary differential equations, partial differential equations, agent-based and rule-based models, etc. These...
3.
Nanda P, Budak M, Michael C, Krupinsky K, Kirschner D
bioRxiv
. 2023 Nov;
PMID: 38014103
Although infectious disease dynamics are often analyzed at the macro-scale, increasing numbers of drug-resistant infections highlight the importance of within-host modeling that simultaneously solves across multiple scales to effectively respond...
4.
Janakiraman S, Engels S, Nanda P, Budak M, Greenstein T, Moraes M, et al.
STAR Protoc
. 2023 Aug;
4(3):102442.
PMID: 37549035
Biosafety level 3 decontamination precautions motivate measuring microbial colonies using consumable photography instead of expensive automated plate counters or smartphones, and assaying drug treatments-with multiple concentrations per treatment, replicates, and...
5.
Budak M, Cicchese J, Maiello P, Jacob Borish H, White A, Chishti H, et al.
PLoS Comput Biol
. 2023 Jun;
19(6):e1010823.
PMID: 37319311
Tuberculosis (TB) continues to be one of the deadliest infectious diseases in the world, causing ~1.5 million deaths every year. The World Health Organization initiated an End TB Strategy that...
6.
Renardy M, Gillen C, Yang Z, Mukasa L, Bates J, Butler R, et al.
PLOS Glob Public Health
. 2023 Mar;
3(2):e0001580.
PMID: 36963087
Tuberculosis (TB) elimination in the United States remains elusive, and community-specific, localized intervention strategies may be necessary to meet elimination goals. A better understanding of the genotypic diversity of Mtb,...
7.
Joslyn L, Flynn J, Kirschner D, Linderman J
Sci Rep
. 2022 Dec;
12(1):20731.
PMID: 36456599
Some persistent infections provide a level of immunity that protects against reinfection with the same pathogen, a process referred to as concomitant immunity. To explore the phenomenon of concomitant immunity...
8.
Grant N, Maiello P, Klein E, Lin P, Jacob Borish H, Tomko J, et al.
Cell Rep
. 2022 May;
39(7):110826.
PMID: 35584684
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a global health concern, yearly resulting in 10 million new cases of active TB. Immunologic investigation of lung granulomas is...
9.
Joslyn L, Linderman J, Kirschner D
J Theor Biol
. 2022 Feb;
539:111042.
PMID: 35114195
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (Mtb), is one of the world's deadliest infectious diseases and remains a significant global health burden. TB disease and pathology can present...
10.
Millar J, Butler J, Evans S, Grant N, Mattila J, Linderman J, et al.
Front Immunol
. 2021 Dec;
12:790557.
PMID: 34880878
[This corrects the article DOI: 10.3389/fimmu.2020.613638.].