Mojgan Aghazadeh Tabrizi
Overview
Explore the profile of Mojgan Aghazadeh Tabrizi including associated specialties, affiliations and a list of published articles.
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82
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1053
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Recent Articles
1.
Aghazadeh Tabrizi M, Baraldi P, Baraldi S, Ruggiero E, De Stefano L, Rizzolio F, et al.
J Med Chem
. 2018 Jan;
61(3):1340-1354.
PMID: 29309142
Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays an important role in the degradation of the endocannabinoid neurotransmitter 2-arachidonoylglycerol, which is implicated in many physiological processes. Beyond the possible...
2.
Jacobson K, Merighi S, Varani K, Borea P, Baraldi S, Aghazadeh Tabrizi M, et al.
Med Res Rev
. 2017 Jul;
38(4):1031-1072.
PMID: 28682469
The A adenosine receptor (A AR) subtype is a novel, promising therapeutic target for inflammatory diseases, such as rheumatoid arthritis (RA) and psoriasis, as well as liver cancer. A AR...
3.
Aghazadeh Tabrizi M, Baraldi P, Baraldi S, Gessi S, Merighi S, Borea P
Med Res Rev
. 2016 Dec;
37(4):936-983.
PMID: 27976413
Transient receptor potential vanilloid 1 (TRPV1) is an ion channel expressed on sensory neurons triggering an influx of cations. TRPV1 receptors function as homotetramers responsive to heat, proinflammatory substances, lipoxygenase...
4.
Romagnoli R, Baraldi P, Prencipe F, Oliva P, Baraldi S, Aghazadeh Tabrizi M, et al.
Sci Rep
. 2016 May;
6:26602.
PMID: 27216165
A novel series of tubulin polymerization inhibitors, based on the 1-(3',4',5'-trimethoxyphenyl)-2-aryl-1H-imidazole scaffold and designed as cis-restricted combretastatin A-4 analogues, was synthesized with the goal of evaluating the effects of various...
5.
Aghazadeh Tabrizi M, Baraldi P, Ruggiero E, Saponaro G, Baraldi S, Poli G, et al.
Eur J Med Chem
. 2016 Feb;
113:11-27.
PMID: 26922225
CB2 cannabinoid receptor ligands are known to be therapeutically important for the treatment of numerous diseases. Recently, we have identified the heteroaryl-4-oxopyridine/7-oxopyrimidine derivatives as highly potent and selective CB2 receptor...
6.
Pinna A, Ko W, Costa G, Tronci E, Fidalgo C, Simola N, et al.
Mov Disord
. 2016 Feb;
31(4):501-11.
PMID: 26871939
Background: The serotonin 5-HT1A/1B receptor agonist eltoprazine suppressed dyskinetic-like behavior in animal models of Parkinson's disease (PD) but simultaneously reduced levodopa (l-dopa)-induced motility. Moreover, adenosine A2A receptor antagonists, such as...
7.
Aghazadeh Tabrizi M, Baraldi P, Borea P, Varani K
Chem Rev
. 2016 Jan;
116(2):519-60.
PMID: 26741146
No abstract available.
8.
Baraldi P, Baraldi S, Saponaro G, Aghazadeh Tabrizi M, Romagnoli R, Ruggiero E, et al.
J Med Chem
. 2015 Jun;
58(13):5355-60.
PMID: 26046697
In this paper we describe an extension SAR study of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine nucleus as A3AR antagonist. Our initial aim was to replace the phenylcarbamoyl moiety at the 5 position of PTP...
9.
Aghazadeh Tabrizi M, Baraldi P, Ruggiero E, Saponaro G, Baraldi S, Romagnoli R, et al.
Eur J Med Chem
. 2015 May;
97:289-305.
PMID: 26002335
Fatty acid amide hydrolase (FAAH) inhibitors have gained attention as potential therapeutic targets in the management of neuropathic pain. Here, we report a series of pyrazole phenylcyclohexylcarbamate derivatives standing on...
10.
Preti D, Baraldi P, Saponaro G, Romagnoli R, Aghazadeh Tabrizi M, Baraldi S, et al.
J Med Chem
. 2015 Mar;
58(7):3253-67.
PMID: 25780876
Stimulation of A2A adenosine receptors (AR) promotes anti-inflammatory responses in animal models of allergic rhinitis, asthma, chronic obstructive pulmonary disease, and rheumatic diseases. Herein we describe the results of a...