» Authors » Pier Andrea Borea

Pier Andrea Borea

Explore the profile of Pier Andrea Borea including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 189
Citations 4117
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Merighi S, Nigro M, Travagli A, Fernandez M, Vincenzi F, Varani K, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684558
Alzheimer's disease (AD) is a neurodegenerative pathology covering about 70% of all cases of dementia. It is associated with neuroinflammation and neuronal cell death, which are involved in disease progression....
2.
Fernandez M, Nigro M, Travagli A, Pasquini S, Vincenzi F, Varani K, et al.
Pharmaceutics . 2023 Oct; 15(10). PMID: 37896201
The blood-brain barrier (BBB) is a biological barrier that protects the central nervous system (CNS) by ensuring an appropriate microenvironment. Brain microvascular endothelial cells (ECs) control the passage of molecules...
3.
Vincenzi F, Pasquini S, Contri C, Cappello M, Nigro M, Travagli A, et al.
Biomolecules . 2023 Sep; 13(9). PMID: 37759787
Adenosine receptors (ARs) are widely acknowledged pharmacological targets yet are still underutilized in clinical practice. Their ubiquitous distribution in almost all cells and tissues of the body makes them, on...
4.
Merighi S, Travagli A, Nigro M, Pasquini S, Cappello M, Contri C, et al.
Biomolecules . 2023 Jun; 13(6). PMID: 37371547
Alzheimer's disease (AD) is the most prevalent kind of dementia with roughly 135 million cases expected in the world by 2050. Unfortunately, current medications for the treatment of AD can...
5.
Corli G, Tirri M, Bilel S, Arfe R, Coccini T, Roda E, et al.
Psychopharmacology (Berl) . 2023 May; 240(7):1435-1452. PMID: 37233813
Rationale: 1-[(5-fluoropentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl) methanone (MAM-2201) is a potent synthetic cannabinoid receptor agonist illegally marketed in "spice" products and as "synthacaine" for its psychoactive effects. It is a naphthoyl-indole derivative which differs...
6.
Pasquini S, Contri C, Cappello M, Borea P, Varani K, Vincenzi F
Front Pharmacol . 2022 Oct; 13:1030895. PMID: 36278183
Adenosine receptors (ARs) have been identified as promising therapeutic targets for countless pathological conditions, spanning from inflammatory diseases to central nervous system disorders, from cancer to metabolic diseases, from cardiovascular...
7.
Tirri M, Arfe R, Bilel S, Corli G, Marchetti B, Fantinati A, et al.
Int J Mol Sci . 2022 Jul; 23(14). PMID: 35887377
3-(1-Naphthalenylmethyl)-1-pentyl-1H-indole (JWH-175) is a synthetic cannabinoid illegally marketed for its psychoactive cannabis-like effects. This study aimed to investigate and compare in vitro and in vivo pharmacodynamic activity of JWH-175 with...
8.
Merighi S, Borea P, Varani K, Vincenzi F, Travagli A, Nigro M, et al.
Molecules . 2022 May; 27(9). PMID: 35566035
The A adenosine receptor is a protein belonging to a family of four GPCR adenosine receptors. It is involved in the regulation of several pathophysiological conditions in both the central...
9.
Merighi S, Nigro M, Travagli A, Pasquini S, Borea P, Varani K, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563447
The A2A adenosine receptor, a member of the P1 purinergic receptor family, plays a crucial role in the pathophysiology of different neurodegenerative illnesses, including Alzheimer’s disease (AD). It regulates both...
10.
Pasquini S, Contri C, Merighi S, Gessi S, Borea P, Varani K, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163142
Adenosine exerts an important role in the modulation of central nervous system (CNS) activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes, adenosine subtly regulates neurotransmission, interfering with...