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Mattan Hurevich

Explore the profile of Mattan Hurevich including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 324
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Recent Articles
1.
Chen L, Medrano Sandonas L, Traber P, Dianat A, Tverdokhleb N, Hurevich M, et al.
Sci Data . 2025 Feb; 12(1):324. PMID: 39987132
We introduce the MORE-Q dataset, a quantum-mechanical (QM) dataset encompassing the structural and electronic data of non-covalent molecular sensors formed by combining 18 mucin-derived olfactorial receptors with 102 body odor...
2.
Alshanski I, Toraskar S, Mor K, Daligault F, Jain P, Grandjean C, et al.
Langmuir . 2024 Oct; 40(42):22152-22158. PMID: 39376038
is a pathogenic bacterium that contains the surface-bound neuraminidase, . has two domains that interact with sialosides. It is hard to determine the contribution of each domain separately on catalysis...
3.
Alshanski I, Toraskar S, Gordon-Levitan D, Massetti M, Jain P, Vaccaro L, et al.
Langmuir . 2024 Mar; 40(14):7471-7478. PMID: 38554266
Neuraminidases (NA) are sialic acid-cleaving enzymes that are used by both bacteria and viruses. These enzymes have sialoside structure-related binding and cleaving preferences. Differentiating between these enzymes requires using a...
4.
Sukhran Y, Alshanski I, Filiba O, Mackintosh M, Schapiro I, Hurevich M
J Org Chem . 2023 Jun; 88(13):9313-9320. PMID: 37269328
Design and synthesis of orthogonally protected monosaccharide building blocks are crucial for the preparation of well-defined oligosaccharides in a stereo- and regiocontrolled manner. Selective introduction of protecting groups to partially...
5.
Bakhatan Y, Alshanski I, Chan C, Lo W, Lu P, Liao P, et al.
Chemistry . 2023 Apr; 29(38):e202300897. PMID: 37035910
Solid phase synthesis is the most dominant approach for the preparation of biological oligomers as it enables the introduction of monomers iteratively. Accelerated solid phase synthesis of biological oligomers is...
6.
Alshanski I, Toraskar S, Shitrit A, Gordon-Levitan D, Jain P, Kikkeri R, et al.
ACS Chem Biol . 2023 Feb; 18(3):605-614. PMID: 36792550
Sialic acid recognition and hydrolysis are essential parts of cellular function and pathogen infectivity. Neuraminidases are enzymes that detach sialic acid from sialosides, and their inhibition is a prime target...
7.
Stern Bauer T, Yakobi R, Hurevich M, Yitzchaik S, Hayouka Z
Sensors (Basel) . 2023 Jan; 23(2). PMID: 36679359
The biosensing of bacterial pathogens is of a high priority. Electrochemical biosensors are an important future tool for rapid bacteria detection. A monolayer of bacterial-binding peptides can serve as a...
8.
Strauss P, Nuti F, Quagliata M, Papini A, Hurevich M
Org Biomol Chem . 2022 Nov; 21(8):1674-1679. PMID: 36385318
Peptide fragments of glycoproteins containing multiple -glycosylated sites are essential biochemical tools not only to investigate protein-protein interactions but also to develop glycopeptide-based diagnostics and immunotherapy. However, solid-phase synthesis of...
9.
Bakhatan Y, Ben Abba Amiel D, Sukhran Y, Chan C, Lo W, Lu P, et al.
Chem Commun (Camb) . 2022 Sep; 58(80):11256-11259. PMID: 36111607
Optimization of glycosylation conditions for automated glycan assembly is highly challenging, demands wasteful use of precious building blocks, and relies on nontrivial analyses. We developed a semi-quantitative method for automated...
10.
Grunhaus D, Rossich Molina E, Cohen R, Stein T, Friedler A, Hurevich M
Org Process Res Dev . 2022 Aug; 26(8):2492-2497. PMID: 36032360
Preparing phosphorylated peptides with multiple adjacent phosphorylations is synthetically difficult, leads to β-elimination, results in low yields, and is extremely slow. We combined synthetic chemical methodologies with computational studies and...