Mary E Napier
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Explore the profile of Mary E Napier including associated specialties, affiliations and a list of published articles.
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29
Citations
1812
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Recent Articles
1.
Bowerman C, Byrne J, Chu K, Schorzman A, Keeler A, Sherwood C, et al.
Nano Lett
. 2016 Dec;
17(1):242-248.
PMID: 27966988
Novel treatment strategies, including nanomedicine, are needed for improving management of triple-negative breast cancer. Patients with triple-negative breast cancer, when considered as a group, have a worse outcome after chemotherapy...
2.
Byrne J, Jajja M, ONeill A, Bickford L, Keeler A, Hyder N, et al.
Sci Transl Med
. 2015 Feb;
7(273):273ra14.
PMID: 25653220
Parenteral and oral routes have been the traditional methods of administering cytotoxic agents to cancer patients. Unfortunately, the maximum potential effect of these cytotoxic agents has been limited because of...
3.
Gharpure K, Chu K, Bowerman C, Miyake T, Pradeep S, Mangala S, et al.
Mol Cancer Ther
. 2014 Apr;
13(7):1750-7.
PMID: 24755199
The purpose of this study was to investigate the antitumor effects of a combination of metronomic doses of a novel delivery vehicle, PLGA-PRINT nanoparticles containing docetaxel, and antiangiogenic mEZH2 siRNA...
4.
Chu K, Finniss M, Schorzman A, Kuijer J, Luft J, Bowerman C, et al.
Nano Lett
. 2014 Feb;
14(3):1472-6.
PMID: 24552251
Delivery systems designed to have triggered release after passively targeting the tumor may improve small molecule chemotherapeutic delivery. Particle replication in nonwetting templates was used to prepare nanoparticles to passively...
5.
Xu J, Luft J, Yi X, Tian S, Owens G, Wang J, et al.
Mol Pharm
. 2013 Aug;
10(9):3366-74.
PMID: 23924216
Herein we report the development of a nonviral lipid-complexed PRINT (particle replication in nonwetting templates) protein particle system (LPP particle) for RNA replicon delivery with a view toward RNA replicon-based...
6.
Jones S, Roberts R, Robbins G, Perry J, Kai M, Chen K, et al.
J Clin Invest
. 2013 Jun;
123(7):3061-73.
PMID: 23778144
Extended circulation of nanoparticles in blood is essential for most clinical applications. Nanoparticles are rapidly cleared by cells of the mononuclear phagocyte system (MPS). Approaches such as grafting polyethylene glycol...
7.
Chu K, Hasan W, Rawal S, Walsh M, Enlow E, Luft J, et al.
Nanomedicine
. 2012 Dec;
9(5):686-93.
PMID: 23219874
From The Clinical Editor: In this study, the plasma, tumor, and tissue pharmacokinetics of different Docetaxel nanoparticles of precise shape and size were characterized in mice with human ovarian carcinoma...
8.
Chen K, Merkel T, Pandya A, Napier M, Luft J, Daniel W, et al.
Biomacromolecules
. 2012 Aug;
13(9):2748-59.
PMID: 22852860
We synthesized extremely deformable red blood cell-like microgel particles and loaded them with bovine hemoglobin (Hb) to potentiate oxygen transport. With similar shape and size as red blood cells (RBCs),...
9.
Merkel T, Chen K, Jones S, Pandya A, Tian S, Napier M, et al.
J Control Release
. 2012 Jun;
162(1):37-44.
PMID: 22705460
There is a growing recognition that the deformability of particles used for drug delivery plays a significant role on their biodistribution and circulation profile. Understanding these effects would provide a...
10.
Kersey F, Merkel T, Perry J, Napier M, DeSimone J
Langmuir
. 2012 May;
28(23):8773-81.
PMID: 22612428
We describe the fabrication of filamentous hydrogel nanoparticles using a unique soft lithography based particle molding process referred to as PRINT (particle replication in nonwetting templates). The nanoparticles possess a...