Luc Schoonjans
Overview
Explore the profile of Luc Schoonjans including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
4605
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Recent Articles
1.
de Zeeuw P, Treps L, Garcia-Caballero M, Harjes U, Kalucka J, De Legher C, et al.
Commun Biol
. 2024 May;
7(1):618.
PMID: 38783087
Endothelial cells (ECs) are highly glycolytic, but whether they generate glycolytic intermediates via gluconeogenesis (GNG) in glucose-deprived conditions remains unknown. Here, we report that glucose-deprived ECs upregulate the GNG enzyme...
2.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, et al.
Signal Transduct Target Ther
. 2023 Aug;
8(1):305.
PMID: 37591843
Although VEGF-B was discovered as a VEGF-A homolog a long time ago, the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups. Notwithstanding, drugs...
3.
Sokol L, Cuypers A, Truong A, Bouche A, Brepoels K, Souffreau J, et al.
Commun Biol
. 2023 Jun;
6(1):648.
PMID: 37330599
Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional...
4.
Geldhof V, de Rooij L, Sokol L, Amersfoort J, De Schepper M, Rohlenova K, et al.
Nat Commun
. 2022 Sep;
13(1):5511.
PMID: 36127427
Since a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC...
5.
de Rooij L, Becker L, Teuwen L, Boeckx B, Jansen S, Feys S, et al.
Cardiovasc Res
. 2022 Aug;
119(2):520-535.
PMID: 35998078
Aims: Severe acute respiratory syndrome coronavirus-2 infection causes COVID-19, which in severe cases evokes life-threatening acute respiratory distress syndrome (ARDS). Transcriptome signatures and the functional relevance of non-vascular cell types...
6.
Conchinha N, Sokol L, Teuwen L, Veys K, Dumas S, Meta E, et al.
STAR Protoc
. 2021 Sep;
2(3):100508.
PMID: 34585146
Endothelial cells (ECs) harbor distinct phenotypical and functional characteristics depending on their tissue localization and contribute to brain, eye, lung, and muscle diseases such as dementia, macular degeneration, pulmonary hypertension,...
7.
Dumas S, Meta E, Conchinha N, Sokol L, Chen R, Borri M, et al.
STAR Protoc
. 2021 Aug;
2(3):100523.
PMID: 34382011
Endothelial cells (ECs) exhibit phenotypic and functional tissue specificities, critical for studies in the vascular field and beyond. Thus, tissue-specific methods for isolation of highly purified ECs are necessary. Kidney,...
8.
Teuwen L, de Rooij L, Cuypers A, Rohlenova K, Dumas S, Garcia-Caballero M, et al.
Cell Rep
. 2021 Jun;
35(11):109253.
PMID: 34133923
Tumor vessel co-option is poorly understood, yet it is a resistance mechanism against anti-angiogenic therapy (AAT). The heterogeneity of co-opted endothelial cells (ECs) and pericytes, co-opting cancer and myeloid cells...
9.
Sokol L, Geldhof V, Garcia-Caballero M, Conchinha N, Dumas S, Meta E, et al.
STAR Protoc
. 2021 May;
2(2):100489.
PMID: 34007969
Endothelial cells (ECs) from the small intestine, colon, liver, and heart have distinct phenotypes and functional adaptations that are dependent on their physiological environment. Gut ECs adapt to low oxygen,...
10.
Leslie J, Macia M, Luli S, Worrell J, Reilly W, Paish H, et al.
Nat Metab
. 2020 Dec;
3(1):118-119.
PMID: 33303984
No abstract available.