Lucas Treps
Overview
Explore the profile of Lucas Treps including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
46
Citations
3257
Followers
0
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Recent Articles
1.
Bourreau C, Navarro E, Cotinat M, Krejbich M, Guillonneau F, Guette C, et al.
Cancer Med
. 2025 Mar;
14(5):e70707.
PMID: 40028673
Aim: The tumor microenvironment (TME) of non-small cell lung cancer (NSCLC) is highly heterogeneous and is involved in tumorigenesis and resistance to therapy. Among the cells of the TME, endothelial...
2.
Lebas M, Chinigo G, Courmont E, Bettaieb L, Machmouchi A, Goveia J, et al.
Sci Adv
. 2024 Aug;
10(32):eadp6182.
PMID: 39121218
Endothelial cells (ECs) are highly plastic, capable of differentiating into various cell types. Endothelial-to-mesenchymal transition (EndMT) is crucial during embryonic development and contributes substantially to vascular dysfunction in many cardiovascular...
3.
Chatelain C, Berland L, Grard M, Jouand N, Fresquet J, Nader J, et al.
Oncoimmunology
. 2024 Jul;
13(1):2377830.
PMID: 39005546
Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or responsiveness. However, other cells in the tumor microenvironment (TME),...
4.
Declercq M, Treps L, Geldhof V, Conchinha N, de Rooij L, Subramanian A, et al.
Liver Int
. 2024 Jun;
44(9):2382-2395.
PMID: 38847551
Background & Aims: Cystic fibrosis (CF) is considered a multisystemic disorder in which CF-associated liver disease (CFLD) is the third most common cause of mortality. Currently, no effective treatment is...
5.
de Zeeuw P, Treps L, Garcia-Caballero M, Harjes U, Kalucka J, De Legher C, et al.
Commun Biol
. 2024 May;
7(1):618.
PMID: 38783087
Endothelial cells (ECs) are highly glycolytic, but whether they generate glycolytic intermediates via gluconeogenesis (GNG) in glucose-deprived conditions remains unknown. Here, we report that glucose-deprived ECs upregulate the GNG enzyme...
6.
Hulo P, Deshayes S, Fresquet J, Chene A, Blandin S, Boisgerault N, et al.
Respir Res
. 2024 Apr;
25(1):156.
PMID: 38581044
Background: Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination with chemotherapy has deeply impacted the therapeutic care leading to an improved overall...
7.
Bourreau C, Treps L, Faure S, Fradin D, Clere N
Pharmacol Ther
. 2023 Jan;
242:108347.
PMID: 36642389
While new targeted therapies have considerably changed the treatment and prognosis of non-small cell lung cancer (NSCLC), they are frequently unsuccessful due to primary or acquired resistances. Chemoresistance is a...
8.
Geldhof V, de Rooij L, Sokol L, Amersfoort J, De Schepper M, Rohlenova K, et al.
Nat Commun
. 2022 Sep;
13(1):5511.
PMID: 36127427
Since a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC...
9.
Treps L, Ager A, Hida K
Front Cell Dev Biol
. 2022 Apr;
10:885670.
PMID: 35425768
No abstract available.
10.
Conchinha N, Sokol L, Teuwen L, Veys K, Dumas S, Meta E, et al.
STAR Protoc
. 2021 Sep;
2(3):100508.
PMID: 34585146
Endothelial cells (ECs) harbor distinct phenotypical and functional characteristics depending on their tissue localization and contribute to brain, eye, lung, and muscle diseases such as dementia, macular degeneration, pulmonary hypertension,...