Signal Transduction and Targeted Therapy
Overview
Signal Transduction and Targeted Therapy is a peer-reviewed scientific journal that focuses on the latest advancements in the field of cellular signaling pathways and their targeted therapeutic applications. It publishes high-quality research articles, reviews, and commentaries, providing a comprehensive platform for researchers and clinicians to explore innovative strategies for treating various diseases by modulating signaling cascades.
Details
Details
Abbr.
Signal Transduct Target Ther
Start
2016
End
Continuing
p-ISSN
2095-9907
e-ISSN
2059-3635
Country
United Kingdom
Language
English
Specialties
Pharmacology
Cell Biology
Cell Biology
Metrics
Metrics
h-index / Ranks: 2345
117
SJR / Ranks: 97
8737
CiteScore / Ranks: 140
31.50
JIF / Ranks: 44
39.3
Recent Articles
1.
Wang Y, Lu J, Chong X, Wang C, Chen X, Peng Z, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):100.
PMID: 40082418
Alpha-fetoprotein-producing gastric or gastro-esophageal junction (AFP-G/GEJ) cancer, a rare gastric cancer subtype, exhibits increased angiogenesis and more immunosuppression than non-AFP-G/GEJ cancer. The potential benefits of anti-angiogenic agents and immunotherapy for...
2.
Kos T, Saur D
Signal Transduct Target Ther
. 2025 Mar;
10(1):86.
PMID: 40082410
No abstract available.
3.
Ma S, Wang Z, Xiong Z, Ge Y, Xu M, Zhang J, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):87.
PMID: 40082405
Enhancer RNAs (eRNAs), a subclass of non-coding RNAs transcribed from enhancer regions, have emerged as critical regulators of gene expression; however, their functional roles in prostate cancer remain largely unexplored....
4.
Gu J, He Y, He C, Zhang Q, Huang Q, Bai S, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):84.
PMID: 40069202
Molecular chaperones, a class of complex client regulatory systems, play significant roles in the prevention of protein misfolding and abnormal aggregation, the modulation of protein homeostasis, and the protection of...
5.
Yu Y, Li Y, Cui R, Yan Y, Li F, Chen Y, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):85.
PMID: 40069155
Large granular lymphocytic leukemia (LGLL) is characterized by the clonal proliferation of cytotoxic T lymphocytes or NK cells. Standard first-line immunosuppressive treatments have limitations, achieving complete remission (CR) rates of...
6.
Jiang Q, Liu J, Huang S, Wang X, Chen X, Liu G, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):76.
PMID: 40059211
In the context of global ageing, the prevalence of neurodegenerative diseases and dementia, such as Alzheimer's disease (AD), is increasing. However, the current symptomatic and disease-modifying therapies have achieved limited...
7.
Liu M, Wang Y, Zhang Y, Hu D, Tang L, Zhou B, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):73.
PMID: 40059188
The ability of small nucleic acids to modulate gene expression via a range of processes has been widely explored. Compared with conventional treatments, small nucleic acid therapeutics have the potential...
8.
Zhou Y, Jiang J, He S, Li Y, Cheng X, Liu S, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):83.
PMID: 40059116
Epstein-Barr virus (EBV) is a significant epigenetic driver in the development of epithelial-origin nasopharyngeal carcinoma (NPC) and gastric cancer (GC), which together represent 80% of EBV-associated malignancies. Despite its known...
9.
Guan F, Wang R, Yi Z, Luo P, Liu W, Xie Y, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):93.
PMID: 40055311
Macrophages are immune cells belonging to the mononuclear phagocyte system. They play crucial roles in immune defense, surveillance, and homeostasis. This review systematically discusses the types of hematopoietic progenitors that...
10.
Ma W, Tang S, Yao P, Zhou T, Niu Q, Liu P, et al.
Signal Transduct Target Ther
. 2025 Mar;
10(1):75.
PMID: 40050633
In recent years, the incidence of acute respiratory distress syndrome (ARDS) has been gradually increasing. Despite advances in supportive care, ARDS remains a significant cause of morbidity and mortality in...