Guy Eelen
Overview
Explore the profile of Guy Eelen including associated specialties, affiliations and a list of published articles.
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Articles
86
Citations
6235
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Recent Articles
1.
Gunther D, Bergerbit C, Marsee A, Vedaraman S, Pueyo-Moliner A, Pueyo Moliner A, et al.
Biofabrication
. 2025 Jan;
17(2).
PMID: 39854847
Bioprinting is currently the most promising method to biofabricate complex tissueswith the potential to transform the future of organ transplantation and drug discovery. Efforts to create such tissues are, however,...
2.
Pozzo E, Yedigaryan L, Giarratana N, Wang C, Garrido G, Degreef E, et al.
Cell Rep
. 2025 Jan;
44(1):115171.
PMID: 39799567
Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, arises in skeletal muscle and remains in an undifferentiated state due to transcriptional and post-transcriptional regulators. Among its subtypes, fusion-negative RMS...
3.
Declercq M, Treps L, Geldhof V, Conchinha N, de Rooij L, Subramanian A, et al.
Liver Int
. 2024 Jun;
44(9):2382-2395.
PMID: 38847551
Background & Aims: Cystic fibrosis (CF) is considered a multisystemic disorder in which CF-associated liver disease (CFLD) is the third most common cause of mortality. Currently, no effective treatment is...
4.
de Zeeuw P, Treps L, Garcia-Caballero M, Harjes U, Kalucka J, De Legher C, et al.
Commun Biol
. 2024 May;
7(1):618.
PMID: 38783087
Endothelial cells (ECs) are highly glycolytic, but whether they generate glycolytic intermediates via gluconeogenesis (GNG) in glucose-deprived conditions remains unknown. Here, we report that glucose-deprived ECs upregulate the GNG enzyme...
5.
Truong A, Becker L, Dekoning N, Bouche A, Veys K, Hosseinkhani B, et al.
MethodsX
. 2023 Nov;
11:102446.
PMID: 37928105
Angiogenesis and lymphangiogenesis, the formation of new blood or lymphatic vessels, respectively, from preexisting vasculature is essential during embryonic development, but also occurs during tissue repair and in pathological conditions...
6.
Sneyers F, Kerkhofs M, Speelman-Rooms F, Welkenhuyzen K, La Rovere R, Shemy A, et al.
Cell Death Dis
. 2023 Sep;
14(9):600.
PMID: 37684238
Intracellular Ca signals control several physiological and pathophysiological processes. The main tool to chelate intracellular Ca is intracellular BAPTA (BAPTA), usually introduced into cells as a membrane-permeant acetoxymethyl ester (BAPTA-AM)....
7.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, et al.
Signal Transduct Target Ther
. 2023 Aug;
8(1):305.
PMID: 37591843
Although VEGF-B was discovered as a VEGF-A homolog a long time ago, the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups. Notwithstanding, drugs...
8.
Sokol L, Cuypers A, Truong A, Bouche A, Brepoels K, Souffreau J, et al.
Commun Biol
. 2023 Jun;
6(1):648.
PMID: 37330599
Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional...
9.
Bissenova S, Ellis D, Callebaut A, Eelen G, Derua R, Buitinga M, et al.
Cells
. 2023 May;
12(9).
PMID: 37174719
Background And Aims: Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by a T-cell-mediated destruction of the pancreatic insulin-producing beta cells. A growing body of evidence suggests that...
10.
Cuypers A, Teuwen L, Bridgeman V, de Rooij L, Eelen G, Dewerchin M, et al.
STAR Protoc
. 2022 Sep;
3(4):101691.
PMID: 36173713
Tumor vessel co-option, a process in which cancer cells "hijack" pre-existing blood vessels to grow and invade healthy tissue, is poorly understood but is a proposed resistance mechanism against anti-angiogenic...