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Judith Murray-Rust

Explore the profile of Judith Murray-Rust including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 814
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Cell Biology
Top 10 Co-Authors
Neil Q McDonald
Phillip P Knowles
Neil McDonald
Shamshad Cockcroft
Svend Kjaer
Farahnaz Movahedzadeh
Mark S B McAlister
Peter J Parker
Andrew Fadden
Matthew Newman
Published In
J Biol Chem
Structure
Mol Microbiol
EMBO J
Bioorg Med Chem
Affiliations
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Recent Articles
11.
Crystallization of the xeroderma pigmentosum group F endonuclease from Aeropyrum pernix
Lally J, Newman M, Murray-Rust J, Fadden A, Kawarabayasi Y, McDonald N
Acta Crystallogr D Biol Crystallogr . 2004 Aug; 60(Pt 9):1658-61. PMID: 15333947
The xeroderma pigmentosa group F protein (XPF) is a founding member of a family of 3'-flap endonucleases that play an essential role in nucleotide-excision repair, DNA replication and recombination. The...
12.
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes
Morgan C, Skippen A, Segui B, Ball A, Allen-Baume V, Larijani B, et al.
J Biol Chem . 2004 Aug; 279(45):47159-71. PMID: 15322105
Phosphatidylinositol transfer protein alpha (PITPalpha) participates in the supply of phosphatidylinositol (PI) required for many cellular events including phospholipase C (PLC) beta and gamma signaling by G-protein-coupled receptors and receptor-tyrosine...
13.
Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol
Tilley S, Skippen A, Murray-Rust J, Swigart P, Stewart A, Morgan C, et al.
Structure . 2004 Feb; 12(2):317-26. PMID: 14962392
Phosphatidylinositol transfer protein alpha (PITPalpha) selectively transports and promotes exchange of phosphatidylinositol (PI) and phosphatidylcholine (PC) between lipid bilayers. In higher eukaryotes PITPalpha is required for cellular functions such as...
14.
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence
Movahedzadeh F, Smith D, Norman R, Dinadayala P, Murray-Rust J, Russell D, et al.
Mol Microbiol . 2004 Feb; 51(4):1003-14. PMID: 14763976
Inositol is utilized by Mycobacterium tuberculosis in the production of its major thiol and of essential cell wall lipoglycans. We have constructed a mutant lacking the gene encoding inositol-1-phosphate synthase...
15.
PKC at a glance
Parker P, Murray-Rust J
J Cell Sci . 2003 Dec; 117(Pt 2):131-2. PMID: 14676268
No abstract available.
16.
S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase
Leiper J, Murray-Rust J, McDonald N, Vallance P
Proc Natl Acad Sci U S A . 2002 Oct; 99(21):13527-32. PMID: 12370443
The enzyme dimethylarginine dimethylaminohydrolase (DDAH) hydrolyses asymmetrically methylated arginine residues that are endogenously produced inhibitors of nitric oxide synthases (NOS). We and others have proposed that DDAH activity is a...
17.
Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis
Norman R, McAlister M, Murray-Rust J, Movahedzadeh F, Stoker N, McDonald N
Structure . 2002 May; 10(3):393-402. PMID: 12005437
Phosphatidylinositol (PI) is essential for Mycobacterium tuberculosis viability and the enzymes involved in the PI biosynthetic pathway are potential antimycobacterial agents for which little structural information is available. The rate-limiting...