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Jeremy P Derrick

Explore the profile of Jeremy P Derrick including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 1647
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Recent Articles
1.
Jones R, Ramirez-Bencomo F, Whiting G, Fang M, Lavender H, Kurzyp K, et al.
PLoS Pathog . 2024 Nov; 20(11):e1012688. PMID: 39541395
Gonorrhoea, caused by Neisseria gonorrhoeae, is a common sexually transmitted infection. Increasing multi-drug resistance and the impact of asymptomatic infections on sexual and reproductive health underline the need for an...
2.
Stejskal L, Thistlethwaite A, Ramirez-Bencomo F, Rashmi S, Harrison O, Feavers I, et al.
Nat Commun . 2024 Aug; 15(1):6712. PMID: 39112489
Development of a vaccine against gonorrhoea is a global priority, driven by the rise in antibiotic resistance. Although Neisseria gonorrhoeae (Ng) infection does not induce substantial protective immunity, highly exposed...
3.
Altarawneh H, Alhomra T, Alharbi M, Fan Y, Derrick J, Xia G
J Antimicrob Chemother . 2024 Jun; 79(7):1677-1682. PMID: 38831599
Objectives: MRSA is a major cause of hospital-acquired and community-acquired infections. Treatment options for MRSA are limited because of the rapid development of β-lactam resistance. Combining antibiotics offers an affordable,...
4.
Walsh L, Clark S, Derrick J, Borrow R
J Infect . 2023 Oct; 87(6):479-489. PMID: 37797844
Objective: Few data outside of individual case reports are available on non-meningococcal, non-gonococcal species of Neisseria as causative agents of invasive disease. This review collates disease, organism and patient information...
5.
Martinez Morales M, van der Walle C, Derrick J
Mol Pharm . 2023 Jun; 20(7):3559-3569. PMID: 37327060
Fibrillation is a challenge commonly encountered in the formulation and development of therapeutic peptides. Cucurbit[7]urils (CB[7]), a group of water soluble macrocycles, have been reported to suppress fibrillation in insulin...
6.
Kulakova A, Augustijn D, El Bialy I, Gentiluomo L, Greco M, Hervo-Hansen S, et al.
Mol Pharm . 2023 May; 20(6):2951-2965. PMID: 37146162
Therapeutic proteins can be challenging to develop due to their complexity and the requirement of an acceptable formulation to ensure patient safety and efficacy. To date, there is no universal...
7.
Viviani V, Fantoni A, Tomei S, Marchi S, Luzzi E, Bodini M, et al.
NPJ Vaccines . 2023 Apr; 8(1):54. PMID: 37045859
The ability of Neisseria meningitidis Outer Membrane Vesicles (OMV) to induce protective responses in humans is well established and mainly attributed to Porin A (PorA). However, the contribution of additional...
8.
Maynard-Smith L, Derrick J, Borrow R, Lucidarme J, Maiden M, Heyderman R, et al.
J Infect Dis . 2022 Nov; 226(12):2204-2214. PMID: 36322504
Background: Neisseria meningitidis serogroup Y, especially ST-23 clonal complex (Y:cc23), represents a larger proportion of invasive meningococcal disease (IMD) in older adults compared to younger individuals. This study explored the...
9.
Chang C, Awanye A, Marsay L, Dold C, Pollard A, Rollier C, et al.
Vaccine . 2022 May; 40(28):3835-3842. PMID: 35610106
Meningococcal meningitis is a rare but serious condition affecting mainly children and young adults. Outer membrane vesicles (OMV) from Neisseria meningitidis have been used successfully as vaccines against the disease,...
10.
Marsay L, Dold C, Paterson G, Yamaguchi Y, Derrick J, Chan H, et al.
J Infect . 2022 Mar; 84(5):658-667. PMID: 35245584
Objective: Adenoviral vectored vaccines, with the appropriate gene insert, induce cellular and antibody responses against viruses, parasites and intracellular pathogens such as Mycobacterium tuberculosis. Here we explored their capacity to...